ENERGY-EXPENDITURE IN HUMANS - EFFECTS OF DIETARY-FAT AND CARBOHYDRATE
ENERGY-EXPENDITURE IN HUMANS - EFFECTS OF DIETARY-FAT AND CARBOHYDRATE
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DOI：
10.1152/ajpendo.1990.258.2.e347
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发表时间：
1990-02-01
影响因子：
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通讯作者：
RAVUSSIN, E
中科院分区：
文献类型：
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作者：
ABBOTT, WGH;HOWARD, BV;RAVUSSIN, E
高膳食脂肪摄入量可能是导致某些人肥胖的重要环境因素。该机制可能是减少能量消耗和/或增加热量摄入。为了确定这些机制的相对重要性，我们用全身热量计测量了 14 名非糖尿病受试者和 6 名非胰岛素依赖型糖尿病受试者的 24 小时能量消耗，这些受试者吃等热量、体重维持、高脂肪和高碳水化合物饮食。所有受试者都是皮马印第安人。在非糖尿病患者中，高脂肪和高碳水化合物饮食的平均 24 小时总能量消耗相似（分别为 2,435 .+-. 103 和 2,359 .+-. 82 kcal/天）。睡眠和静息代谢率、食物的热效应和自发体力活动的平均值没有变化。在糖尿病受试者中也获得了类似的结果。总之，使用全身热量计，我们没有发现高脂肪饮食与高碳水化合物饮食相比 24 小时能量消耗减少的证据。
A high-dietary fat intake may be an important environmental factor leading to obesity in some people. The mechanism could be either a decrease in energy expenditure and/or an increase in caloric intake. To determine the relative importance of these mechanisms we measured 24-h energy expenditure in a whole body calorimeter in 14 nondiabetic subjects and in six subjects with non-insulin-dependent diabetes mellitus, eating isocaloric, weight-maintenance, high-fat, and high-carbohydrate diets. All subjects were Pima Indians. In nondiabetics, the mean total 24-h energy expenditure was similar (2,435 .+-. 103 vs. 2,359 .+-. 82 kcal/day) on high-fat and high-carbohydrate diets, respectively. The means for sleeping and resting metabolic rates, thermic effect of food, and spontaneous physical activity were unchanged. Similar results were obtained in the diabetic subjects. In summary, using a whole body calorimeter, we found no evidence of a decrease in 24-h energy expenditure on a high-fat diet compared with a high-carbohydrate diet.