On the nature of objective and perceived cognitive impairments in depressive symptoms and real-world functioning in young adults

On the nature of objective and perceived cognitive impairments in depressive symptoms and real-world functioning in young adults
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DOI:
10.1016/j.psychres.2020.112932
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发表时间:
2020-05-01
影响因子:
11.3
通讯作者:
Zakzanis, Konstantine K.
Zakzanis, Konstantine K.
中科院分区:
医学2区
文献类型:
--
作者:
Dhillon, Sonya;Videla-Nash, Grace;Zakzanis, Konstantine K.

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抑郁症的认知障碍会导致残疾。根据流行的认知理论,一个人与认知能力相关的感知可能导致并维持抑郁症以及相关结果。在这里,我们研究了感知认知障碍在多大程度上预测了客观神经认知之外的功能障碍。年轻人样本(n = 123)完成了一系列测试,测量客观认知能力、感知认知功能(例如,感知缺陷问卷)、残疾(例如,世界卫生组织残疾评估表)和抑郁症状(贝克抑郁量表-2)。分层多元回归分析测试了感知认知障碍在神经心理学测试指标和与抑郁症相关的残疾之外的解释的增量方差。结果表明,感知到的认知障碍是神经心理学测试分数之外抑郁症状显着增量变化的原因;残疾测量与抑郁症状显着相关,认知障碍也是如此。患有抑郁症和相关疾病的个体更有可能报告认知障碍并经历认知能力下降 - 相对于健康对照,无论客观障碍如何,强调考虑、测量和治疗这种感知认知障碍的重要性,即认知障碍偏差(Dhillon 和 Zakzanis,2019)。
Cognitive impairments in depression contribute to disability. According to prevailing cognitive theories, one's perception related to cognitive ability can cause and maintain depression, and related outcomes. Here, we investigate the degree to which perceived cognitive impairment predicts functional impairment above and beyond objective neurocognition. A sample of young adults (n = 123) completed a battery of tests measuring objective cognitive ability, perceived cognitive function (e.g., Perceived Deficits Questionnaire), disability (e.g., World Health Organization Disability Assessment Schedule) and depressive symptoms (Beck Depression Inventory-2). Hierarchical multiple regression analyses tested the incremental variance that perceived cognitive impairment accounts for above and beyond neuropsychological test measures and disability related to depression. Results show that perceived cognitive impairment accounts for significant incremental variance in depressive symptoms beyond neuropsychological test scores; disability measures were significantly associated with depressive symptoms, as was perceived cognitive impairment. Individuals with depression and related disorders are more likely to report cognitive impairments and experience diminished cognitive ability - relative to healthy controls regardless of objective impairments, highlighting the importance of considering, measuring, and treating this perceived cognitive impairment, that is, Cognitive Impairment Bias (Dhillon and Zakzanis,2019).