Osseointegration of Ti6A14V alloy implants coated with titanium nitride by a new method
Osseointegration of Ti6A14V alloy implants coated with titanium nitride by a new method
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DOI：
10.1302/0301-620x.82b2.9819
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发表时间：
2000-03-01
影响因子：
--
通讯作者：
Gotman, I
中科院分区：
文献类型：
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作者：
Sovak, G;Weiss, A;Gotman, I
Coating titanium alloy implants with titanium nitride (TIN) by the method of Powder Immersion Reaction Assisted Coating (PIRAC) produces a stable layer on their surface. We have examined the ability of the new TIN coating to undergo osseointegration, We implanted TiN-coated and uncoated Ti6Al4V alloy pins into the femora of six-month-old female Wistar rats.SEM after two months showed a bone collar around both TiN-coated and uncoated implants. Morphometrical analysis revealed no significant differences between the percentage of the implant-bone contact and the area and volume of the bone around TiN-coated compared with uncoated implants. Electron-probe microanalysis indicated the presence of calcium and phosphorus at the implant-bone interface. Mineralisation around the implants was also confirmed by labelling with oxytetracycline. Strong activity of alkaline phosphatase and weak activity of tartrate-resistant acid phosphatase were shown histochemically. Very few macrophages were detected by the non-specific esterase reaction at the site of implantation.Our findings indicate good biocompatibility and bone-bonding properties of the new PIRAC TIN coatings which are comparable to those of uncoated Ti6Al4V alloy implants.
