EQUILIBRIUM SWELLING BEHAVIOR OF PH-SENSITIVE HYDROGELS
EQUILIBRIUM SWELLING BEHAVIOR OF PH-SENSITIVE HYDROGELS
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DOI：
10.1016/0009-2509(91)80177-z
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发表时间：
1991-01-01
影响因子：
4.7
通讯作者：
PEPPAS, NA
中科院分区：
文献类型：
--
作者：
BRANNONPEPPAS, L;PEPPAS, NA
采用基于Flory-Huggins热力学理论、橡胶弹性理论及其离子相互作用偏差的新结构模型，研究了水凝胶对pH或离子强度变化敏感的平衡膨胀行为。交联之间的平均分子量数与平衡膨胀特性、聚合物-膨胀剂体系的热力学相容性、离子电荷、可电离聚合物部分的pK(a)以及周围介质的pH和离子强度有关。该模型具有预测、关联和设计能力。
The equilibrium swelling behavior of hydrogels sensitive to pH or ionic strength changes of the swelling medium was studied using new structural models which are based on the Flory-Huggins thermodynamic theory, the rubber elasticity theory, and ionic interaction deviations therefrom. The number average molecular weight between crosslinks was related to equilibrium swelling characteristics, the thermodynamic compatability of the polymer-swelling agent system, the ionic charges, the pK(a) of the ionizable polymer moieties, and the pH and ionic strength of the surrounding medium. The models have predictive, correlative and design capabilities.