SIMULTANEOUS RECORDING OF INPUT AND OUTPUT OF LATERAL GENICULATE NEURONES
SIMULTANEOUS RECORDING OF INPUT AND OUTPUT OF LATERAL GENICULATE NEURONES
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DOI：
10.1038/newbio231191a0
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发表时间：
1971-01-01
期刊：
影响因子：
--
通讯作者：
LEVICK, WR
中科院分区：
文献类型：
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作者：
CLELAND, BG;DUBIN, MW;LEVICK, WR
为了了解猫外侧膝状体背侧核（LGN）处理视觉信息的方式，了解单个LGN神经元的视网膜输入的数量和类型将是有用的。使用视神经的电刺激，Bishop等人得出结论，单个视神经纤维中的脉冲足以激发单个LGN神经元。Creutzfeldt认为LGN神经元可能由一个或几个视网膜神经节细胞驱动。Hubel和Wiesel4提出了基于感受野分析的几种视网膜输入在单个LGN神经元上的会聚模型。Guillery 5提出的解剖学证据表明，某些类型的LGN神经元接受来自几种不同视网膜纤维的输入。现在，我们报告的直接观察，同时记录从单个LGN神经元和单个视网膜神经节细胞提供兴奋性输入给他们。我们将不考虑抑制性影响，这是目前正在研究的。
TO understand the way in which the cat dorsal lateral geniculate nucleus (LGN) processes visual information it would be useful to know the number and type of retinal inputs to individual LGN neurones. Using electrical stimulation of the optic nerve Bishopet al.1concluded that an impulse in a single optic nerve fibre is sufficient to excite a single LGN neurone. From the appearance of excitatory postsynaptic potentials (EPSPs) recorded essentially intracellularly, Creutzfeldt suggested that LGN neurones are driven by perhaps one2or a few3retinal ganglion cells. Hubel and Wiesel4proposed models of convergence of several retinal inputs on single LGN neurones based on analyses of receptive fields. Guillery5produced anatomical evidence that some types of LGN neurones receive inputs from several different retinal fibres. Now we report direct observations which were made by recording simultaneously from single LGN neurones and from individual retinal ganglion cells which provided excitatory input to them. We shall not consider inhibitory influences, which are currently under study.