INHIBITION OF NURSING-INDUCED AND STRESS-INDUCED FALL IN PITUITARY PROLACTIN CONCENTRATION IN LACTATING RATS BY INJECTION OF ACID EXTRACTS OF BOVINE HYPOTHALAMUS.
INHIBITION OF NURSING-INDUCED AND STRESS-INDUCED FALL IN PITUITARY PROLACTIN CONCENTRATION IN LACTATING RATS BY INJECTION OF ACID EXTRACTS OF BOVINE HYPOTHALAMUS.
复制标题
注射牛下丘脑酸性提取物抑制哺乳大鼠垂体催乳素浓度的下降。
DOI:
10.1210/endo-76-5-883
复制
发表时间:
1965
期刊:
影响因子:
4.8
通讯作者:
R. Nallar
中科院分区:
文献类型:
--
作者:
C. Grosvenor;S. Mccann;R. Nallar
The concentration of prolactin in the anterior pituitary glands of lactating rats killed with either ether or Nembutal after 10 ½ hr of isolation from their litters averaged 0.073 IU/mg (prenursed level). Thirty min of nursing, laparotomy with bleeding from the inferior vena cava during 5 min of ether anesthesia, and the stress of cervical stunning followed by decapitation, each reduced the pituitary prolactin concentration significantly below the prenursed level. Nembutal prevented the fall of prolactin concentration which resulted from laparotomy and bleeding. Nursing, followed by ether anesthesia and the stress of laparotomy and bleeding, did not lower pituitary prolactin content more than nursing alone. Injections of acid extracts of bovine stalk-median-eminence (1 SME/rat) inhibited the fall in prolactin concentration which followed the combined stimuli of nursing and stress. Treatment with extracts of bovine cerebral cortex, or with ovine prolactin (12 mg), did not. These results provide in vivo evi...