Anxiety sensitivity and depression in multiple chemical sensitivities and asthma.
Anxiety sensitivity and depression in multiple chemical sensitivities and asthma.
复制标题
多种化学敏感性和哮喘中的焦虑敏感性和抑郁症。
DOI：
10.1097/00043764-200210000-00006
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发表时间：
2002
影响因子：
3.2
通讯作者：
Fiedler,Nancy
中科院分区：
文献类型：
--
作者：
Caccappolo-vanVliet,Elise;Kelly-McNeil,Kathie;Natelson,Benjamin;Kipen,Howard;Fiedler,Nancy
对多种化学物质敏感的患者报告有认知功能障碍、呼吸窘迫和情绪障碍的症状。对30名多重化学敏感性（MCS）患者、19名哮喘患者和31名健康对照者的终生和当前精神疾病、与症状报告相关的人格特征和认知功能测试进行了比较。相对于哮喘患者和对照组，更多MCS受试者符合当前抑郁和躯体化障碍的标准。MCS受试者和哮喘患者在化学气味不耐受和焦虑敏感性量表上的得分明显高于对照组，这两者都是身体症状的重要预测因子。客观神经心理测试差异不大。然而，伴有抑郁症的MCS受试者在言语记忆测试中的表现明显差于哮喘患者，而不是对照组。焦虑和抑郁是MCS受试者身体和认知症状的重要因素。[J] .中华医学杂志，2002;44:890-901。
Patients with sensitivities to multiple chemicals report symptoms of cognitive dysfunction, respiratory distress, and mood disturbance. Lifetime and current psychiatric disorders, personality traits associated with symptom reporting, and tests of cognitive function were compared between 30 subjects with Multiple Chemical Sensitivities (MCS), 19 asthmatics, and 31 healthy controls. Relative to asthmatics and controls, more MCS subjects met criteria for current depression and somatization disorder. MCS subjects and asthmatics scored significantly higher than controls on scales of chemical odor intolerance and anxiety sensitivity, both of which were significant predictors of physical symptoms. Few differences on objective neuropsychological tests were noted. However, MCS subjects with comorbid depression performed significantly worse on a verbal memory test relative to asthmatics but not to controls. Anxiety and depression are significant contributors to the physical and cognitive symptoms of MCS subjects.(J Occup Environ Med. 2002; 44: 890–901)