Chemical irritation of the prostate sensitizes P2X3 receptor‐mediated responses in rat dorsal root ganglion neurons

Chemical irritation of the prostate sensitizes P2X3 receptor‐mediated responses in rat dorsal root ganglion neurons
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DOI:
10.1002/nau.21060
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发表时间:
2011-04
影响因子:
2
通讯作者:
Heng Zhang;Limei Liu;Gensheng Lu;Zhimin Chen;Q. Fang;Zhong Yang;Longkun Li;Weibing Li;B. Song;Zhansong Zhou
Heng Zhang;Limei Liu;Gensheng Lu;Zhimin Chen;Q. Fang;Zhong Yang;Longkun Li;Weibing Li;B. Song;Zhansong Zhou
中科院分区:
医学3区
文献类型:
--
作者:
Heng Zhang;Limei Liu;Gensheng Lu;Zhimin Chen;Q. Fang;Zhong Yang;Longkun Li;Weibing Li;B. Song;Zhansong Zhou

文献摘要

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背根神经节(DRG)伤害感受神经元中的P2X3(ATP门控受体)参与疼痛信号从外周到脊髓的传递。然而,P2X3受体在慢性前列腺疼痛和持续顽固性疼痛中的作用仍不清楚。
P2X3 (ATP‐gated receptors) in nociceptive neurons of dorsal root ganglion (DRG) participate in transmission of pain signals from the periphery to the spinal cord. However, the role of P2X3 receptors in chronic prostate pain and continued intractable pain remains unclear.