An improved synthesis of 6-o-methyl-scutellarein through selective benzylation
An improved synthesis of 6-o-methyl-scutellarein through selective benzylation
复制标题
DOI：
10.3184/174751915x14452625043383
复制
发表时间：
2015-11-01
影响因子：
1.4
通讯作者：
Shi, Zhi-Hao
中科院分区：
文献类型：
--
作者：
Zhang, Wei;Dong, Ze-Xi;Shi, Zhi-Hao
报道了6-O-甲基-灯盏花素的改进合成方法。选用溴化苄基保护灯盏花素中的C-4‘和C-7位羟基。然后对产物进行甲基化和去保护，分四步高产率地生产目标化合物。
An improved synthesis of 6-O-methyl-scutellarein is described. Benzyl bromide was selected to protect both the hydroxyl groups at C-4' and C-7 in scutellarein. The product was then methylated and deprotected to produce the target compound in high yield in four steps.