Predictive factors for metachronous recurrence of early gastric cancer after endoscopic treatment
Predictive factors for metachronous recurrence of early gastric cancer after endoscopic treatment
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DOI：
10.1097/00004836-199907000-00011
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发表时间：
1999-07-01
影响因子：
2.9
通讯作者：
Kinoshita, Y
中科院分区：
文献类型：
--
作者：
Arima, N;Adachi, K;Kinoshita, Y
由于内镜治疗已被评估，并成为建立作为治疗早期胃癌，异时复发已成为一个主要问题。在这份报告中，使用Kaplan-Meier方法和考克斯比例风险回归模型对76例接受内镜治疗的患者的复发预测因素进行了研究。有48名男性和28名女性，年龄为69.6 ± 8.3岁（平均值±标准差），其中5人有同步多发性病变，71人在初始内镜治疗期间发现单一病变。在所有患者中，治疗后通过内窥镜进行定期随访超过2年。76例患者中有55例进行了幽门螺杆菌感染评估，43例阳性，12例阴性。异时性复发在初次治疗时发现同步多发病灶的患者中明显更常见。此外，年龄对复发有积极影响。然而，H.S.和H. pylori感染与异时复发无明显关系。
Since endoscopic treatment has been evaluated and become established as treatment for early gastric cancer, metachronous recurrence has become a major problem. In this report, predictive factors for recurrence were studied using the Kaplan-Meier method and Cox's proportional hazards regression model in 76 patients who received endoscopic treatment. There were 48 men and 28 women age 69.6 +/- 8.3 years (mean +/- standard deviation), 5 of whom had synchronous multiple lesions and 71 who had a single lesion found during the initial endoscopic treatment. In all patients, periodic follow-ups were performed by endoscopy for more than 2 years after treatment. Helicobacter pylori infection was assessed in 55 of the 76 patients, and proved positive in 43 and negative in 12. Metachronous recurrence was detected significantly more frequently in patients whose synchronous multiple lesions were found during the initial treatment. In addition, age affected the recurrence positively. However, Sender and H. pylori infection had no significant relationship with metachronous recurrence.