Regeneration and enlargement of jaw bone using guided tissue regeneration
Regeneration and enlargement of jaw bone using guided tissue regeneration
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DOI：
10.1034/j.1600-0501.1990.010104.x
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发表时间：
1990-12-01
影响因子：
4.3
通讯作者：
Nyman, S.
中科院分区：
文献类型：
--
作者：
Buser, D.;Braegger, U.;Nyman, S.
本研究的目的是介绍引导组织再生（GTR）治疗的手术程序和临床结果，旨在在牙槽嵴解剖结构不允许放置牙科种植体的情况下再生局部颌骨。选择12例患者进行牙槽嵴扩大或骨缺损再生。在指定的区域中，将一个联合的劈裂和全层皮瓣抬高，以用于随后的种植体植入。在皮质骨穿孔以产生出血骨表面之后，将PTEE膜调整到手术部位，使得在膜和下颌骨表面之间产生隔离空间，以增加脊的宽度或再生存在的骨缺损。强调软组织瓣的完全无张力闭合。愈合6 - 10个月后，进行重新开放手术，并评估骨尺寸的增加。在9名患者的12个潜在种植体部位中，获得了足够的骨体积，以允许随后的种植体植入。新骨形成的增益在1.5和5.5 mm之间变化。在3例患者中，急性感染的发展，需要早期去除膜，没有骨再生可以实现。研究结果表明，在无并发症愈合的前提下，GTR的生物学原理对于牙槽嵴扩大或缺损再生具有高度的可预测性。
The purpose of this study was to present the surgical procedures and the clinical results of guided tissue regeneration (GTR) treatment aimed at regenerating local jaw bone in situations where the anatomy of the ridge did not allow the placement of dental implants. 12 patients were selected for ridge enlargement or bony defect regeneration. A combined split- and full-thickness flap was raised in areas designated for subsequent implant placement. Following perforation of the cortical bone to create a bleeding bone surface, a PTEE membrane was adjusted to the surgical site in such a way that a secluded space was created between the membrane and the subjacent bone surface in order to increase the width of the ridge or to regenerate bony defects present. Complete tension-free closure of the soft tissue flap was emphasized. Following a healing period of 6 to 10 months, reopening procedures were performed and the gain of bone dimension was assessed. In 9 patients with 12 potential implant sites, a sufficient bone volume was obtained to allow subsequent implant placement. The gain of new bone formation varied between 1.5 and 5.5 mm. In 3 patients, acute infections developed which necessitated early removal of the membranes and no bone regeneration could be achieved. The results of the study indicate that the biological principle of GTR is highly predictable for ridge enlargement or defect regeneration under the prerequisite of a complication-free healing.