Torsional Mechanics of the Left Ventricle in Patients After Surgical Repair of Tetralogy of Fallot
Torsional Mechanics of the Left Ventricle in Patients After Surgical Repair of Tetralogy of Fallot
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DOI：
10.1253/circj.cj-10-1253
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发表时间：
2011-07-01
影响因子：
3.3
通讯作者：
Cheung, Eddie W. Y.
中科院分区：
文献类型：
--
作者：
Cheung, Yiu-fai;Wong, Sophia J.;Cheung, Eddie W. Y.
背景：本研究旨在验证法洛四联症(TOF)修补术后左室扭转力学改变与右室容量超负荷及左室构型改变的关系。方法与结果：55例年龄19.0±8.1岁的法洛四联症患者和27例年龄匹配的健康对照。用三维超声心动图测量左、右室容量，用舒张期偏心指数(EL)量化左室几何构型。斑点追踪技术测定左心室收缩期峰扭转、舒张期扭转和舒张期扭转速度。与对照组相比，患者右室收缩末期显著增大(P
Background: This study aimed to test the hypothesis that alteration of left ventricular (LV) torsional mechanics occurs in patients after repair of tetralogy of Fallot (TOF) and is associated with right ventricular (RV) volume overload and changes in LV configuration.Methods and Results: Fifty-five TOF patients aged 19.0 +/- 8.1 years and 27 age-matched healthy controls were studied. The LV and RV volumes were measured using 3-dimensional echocardiography while LV geometry was quantified by the diastolic eccentricity index (El). The LV peak systolic torsion and systolic twisting and diastolic untwisting velocities were determined by speckle tracking. Compared with controls, patients had significantly greater RV end-systolic (P