The effects of chronic metabolic acidosis on patterns of protein synthesis in rat renal cortex.
The effects of chronic metabolic acidosis on patterns of protein synthesis in rat renal cortex.
复制标题
慢性代谢性酸中毒对大鼠肾皮质蛋白质合成模式的影响。
DOI:
10.1016/0305-0491(84)90012-9
复制
发表时间:
1984
期刊:
影响因子:
--
通讯作者:
Simpson,DP
中科院分区:
文献类型:
--
作者:
Haas,MJ;Simpson,DP
In the rat chronic metabolic acidosis increases the net synthesis of 17 renal cortex proteins by amounts ranging from 1.5 to 4.5-fold. These proteins have molecular weights between 13,000 and 42,000 and isoelectric points between approximately 5.5 and 7.0. No new proteins not also present in normal animals are detected in renal cortex samples from acidotic animals. Three proteins undergo substantial reductions in their net synthetic rates in chronic metabolic acidosis. On the basis of their physical properties and similar alterations in net synthetic rate in acidosis some of these proteins appear to be closely related and may be coordinately expressed in the rat kidney.
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DOI:
10.1172/jci106314
发表时间:
1970
期刊:
The Journal of clinical investigation
影响因子:
--
作者:
G. Alleyne
通讯作者:
G. Alleyne
影响因子:
4.8
作者:
P. Iynedjian;F. Ballard;R. Hanson
通讯作者:
R. Hanson
影响因子:
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作者:
David M. Parry;J. Brosnan
通讯作者:
J. Brosnan
影响因子:
64.8
作者:
L. Goldstein
通讯作者:
L. Goldstein
DOI:
10.1016/s0021-9258(18)50539-1
发表时间:
1979
期刊:
The Journal of biological chemistry
影响因子:
--
作者:
V. Clark;N. Curthoys
通讯作者:
N. Curthoys