Contribution of Hindpaw Cutaneous Inputs to the Control of Lateral Stability During Walking in the Cat
Contribution of Hindpaw Cutaneous Inputs to the Control of Lateral Stability During Walking in the Cat
复制标题
DOI：
10.1152/jn.00445.2009
复制
发表时间：
2009-09-01
影响因子：
2.5
通讯作者：
Misiaszek, J. E.
中科院分区：
文献类型：
--
作者：
Bolton, D. A. E.;Misiaszek, J. E.
博尔顿DA，Misiaszek JE.猫行走期间后爪皮肤输入对侧向稳定性控制的贡献J Neurophysiol 102：1711-1724，2009。首次发表于2009年7月15日; doi：10.1152/jn.00445.2009。为了描述步行过程中爪子皮肤反馈在平衡调节中的作用，我们比较了猫在后爪皮肤去神经支配之前和之后对侧向支撑表面平移的校正反应。此外，我们还比较了去神经之前和之后不受干扰行走的特征。收集了三只猫的肌电和运动学数据，这些猫被训练穿过人行道，人行道的中心部分可能会意外地横向平移。在去神经支配后，所有的猫都改变了它们的步宽，降低了它们的骨盆，并且在穿过走道时用后腿双支撑花了更多的时间。当被侧向支撑表面平移移位时，失神经支配的猫进行更大的侧向步骤，并且需要多于一个步骤来恢复平衡。然而，没有一只猫在去神经后跌倒。的外观和延迟的反应引起的后腿肌肉的扰动不受去神经支配。然而，这些反应的幅度受到皮肤输入损失的影响。在爪接触引起的反应显着减少，在大多数肌肉中的皮肤输入的情况下，而在立场结束时引起的反应显示臀中肌活动的显着增加，对其他肌肉的活动影响不大。因此，皮肤输入的损失导致步态不稳定。虽然皮肤的反馈，从后爪是不是必不可少的触发纠正反应，以支持表面的干扰，看来，皮肤的输入是重要的缩放响应发起的其他线索。
Bolton DA, Misiaszek JE. Contribution of hindpaw cutaneous inputs to the control of lateral stability during walking in the cat. J Neurophysiol 102: 1711-1724, 2009. First published July 15, 2009; doi:10.1152/jn.00445.2009. To delineate the role of cutaneous feedback from the paws in the regulation of balance during walking, we compared the corrective responses of cats to lateral support surface translation before and after cutaneous denervation of the hindpaws. In addition, we compared characteristics of undisturbed walking before and after denervation. Electromyographic and kinematic data were collected from three cats trained to walk across a walkway, the central portion of which could be unexpectedly translated laterally in either direction. Following denervation, all of the cats changed their step width, lowered their pelvis, and spent more time with the hindlegs in double-support when walking across the walkway. When displaced by lateral support surface translations, the denervated cats made larger lateral steps and required more than a single step to regain balance. However, none of the cats fell following the denervation. The appearance and latency of the responses evoked in the hindleg muscles by the perturbations were unaffected by the denervation. However, the amplitude of these responses was affected by the loss of cutaneous inputs. Responses evoked at paw contact were significantly reduced in most muscles in the absence of cutaneous input, whereas responses evoked at end of stance revealed significant increases in gluteus medius activity with little influence on the activity of other muscles. Therefore the loss of cutaneous inputs leads to instability during gait. Although cutaneous feedback from the hindpaws is not essential for triggering corrective responses to support surface disturbances, it appears that cutaneous inputs are important for scaling the responses initiated by other cues.