Systematic review of pregnancy and neonatal health outcomes associated with exposure to e-waste
Systematic review of pregnancy and neonatal health outcomes associated with exposure to e-waste
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对与接触电子废物相关的妊娠和新生儿健康结果进行系统审查
DOI：
10.1080/10643389.2020.1788913
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发表时间：
2020
影响因子：
12.6
通讯作者：
Yuanyuan Tang
中科院分区：
文献类型：
--
作者：
Narendra Singh;Ogunseitan Oladele A;Yuanyuan Tang
电子废物是世界上增长最快的危险固体废物类别，对许多发展中国家和转型期国家的回收员、拾荒者和废物处置场附近社区的居民构成严重的健康风险。电子垃圾中的有毒成分与各种不利的健康后果有关。这项研究的目的是评估电子垃圾暴露对妊娠结局和新生儿健康的影响。我们系统地在三个电子数据库中搜索原始全文文章，分别是Web of Science，ProQuest Health and Medical数据库和Google Scholar，查找与电子垃圾、妊娠结局和新生儿健康有关的出版物。大多数研究的结果表明，暴露于电子垃圾和怀孕与不利的新生儿健康结果之间可能存在关联，包括婴儿生长的性别差异、毒物的胎盘转移、甲状腺激素干扰、DNA甲基化和氧化损伤、ALAD基因型别、致癌风险以及孕妇和发育中胎儿的性激素干扰。这一结果支持了电子垃圾暴露与对怀孕和新生儿健康结果的负面影响相关的证据。然而，需要改进流行病学调查的设计，以及来自南亚、非洲和拉丁美洲的更多调查来证实这些联系。
Electronic waste (e-waste), the world’s fastest-growing category of hazardous solid waste, poses a serious health risk for recyclers, scavenger workers, and residents of communities near waste disposal sites in many countries with developing economies and those in transition. The toxic components of e-waste have been linked to various adverse health outcomes. The objective of this study was to assess the effects of e-waste exposures on pregnancy outcomes and neonate’s health. We systematically searched original full-length articles in three electronic databases namely Web of Science, ProQuest health and medical databases, and Google Scholar for publications related to e-waste and pregnancy outcomes and neonate’s health. Outcomes from most study showed possible association between exposure to e-waste and pregnancy and adverse neonatal health outcomes including sex-specific differences in infants’ growth, placental transfer of toxicants, thyroid hormones disruption, DNA methylation and oxidative damage, ALAD genotypes, carcinogenic risks, and sex hormones disruption in pregnant women and developing fetus. The results support evidence that e-waste exposure is associated with negative effects on pregnancy and neonatal health outcomes. However, improvements in the design of epidemiological investigations, and more investigations from South Asia, Africa, and Latin America are needed to confirm these associations.