Forensic Pathological Study of 1656 Cases of Sudden Cardiac Death in Southern China.
Forensic Pathological Study of 1656 Cases of Sudden Cardiac Death in Southern China.
复制标题
华南地区1656例心源性猝死的法医病理学研究。
DOI：
10.1097/md.0000000000002707
复制
发表时间：
2016-02
期刊：
影响因子：
1.6
通讯作者：
Cheng J
中科院分区：
文献类型：
--
作者：
Wu Q;Zhang L;Zheng J;Zhao Q;Wu Y;Yin K;Huang L;Tang S;Cheng J
突然的心脏死亡（SCD）正在逐步确定世界各地的年轻人的生活。为了研究SCD的确切病因分布和流行病学特征。这些突然的死亡案件中有43.0％的案例（可访问定义年龄的数据）的平均年龄为38.2岁）。在医院（46.3％）和家里（33.8％）。心肌炎（11.8％）。根据与CAD相关的SCD病例的解剖学检查，冠状动脉伪像的比例超过75％（IV级）为67.2％。动脉，左前降枝是动脉粥样硬化的最容易发生的。冠状动脉的多个分支的病变与衰老有关。
Sudden cardiac death (SCD) is progressively threatening the lives of young people throughout the world. We conducted a retrospective study of SCD cases identified among sudden death cases based on comprehensive autopsies and pathological examinations in the Center for Medicolegal Expertise of Sun Yat-Sen University to investigate the exact etiological distribution and epidemiological features of SCD. One thousand six hundred fifty-six cases were identified, and SCD accounted for 43.0% of these sudden death cases. The mean age of the SCD cases—where the data of definite ages were accessible—was 38.2 years, and the highest incidence occurred among the 31- to 40-year-old cases (25.6%). The male-to-female ratio among SCD cases was 4.3:1, and this ratio peaked in the 41- to 50-year-old group (7.7:1). The places of death were confirmed in 1411 cases, and predominantly in hospitals (46.3%) and at home (33.8%). SCD occurred throughout the year with a marginally increase in April and May. The major causes of SCD were coronary atherosclerotic disease (CAD, 41.6%), unexplained sudden death (15.1%), and myocarditis (11.8%). Our data indicated that in the age group of younger affected persons (below 35 years old), sudden unexplained death and myocarditis were much more prevalent than CAD. According to anatomical examinations of the CAD-related SCD cases, the proportion of cases with coronary artery stenosis exceeding 75% (grade IV) was 67.2%. Moreover, the percentages of higher grades of coronary atherosclerosis increased with age. Among all branches of the coronary arteries, the left anterior descending branch was the most prone to atherosclerosis; atherosclerosis was present in this branch in 95.4% of the cases with atherosclerosis. Additionally, lesions of multiple branches of the coronary artery were associated with ageing. This is the first study to report the causes of death and basic epidemiological data related to SCD in Southern China.