PROJECTIONS OF CELLS IN DIFFERENT LAYERS OF CATS VISUAL-CORTEX
PROJECTIONS OF CELLS IN DIFFERENT LAYERS OF CATS VISUAL-CORTEX
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DOI：
10.1002/cne.901630106
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发表时间：
1975-01-01
影响因子：
2.5
通讯作者：
KELLY, JP
中科院分区：
文献类型：
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作者：
GILBERT, CD;KELLY, JP
用辣根过氧化物酶逆行传递法研究了猫大脑皮质视区不同层细胞的投射。酶的注射是通过记录的微型移液管进行的，这使得有可能通过生理标准定位注射部位。我们发现VI层细胞投射到外侧膝状核，而V层细胞投射到上丘。II和III层的细胞是同侧皮质-皮质联系的主要来源。这种投射模式从一个视觉区域到另一个视觉区域是一致的。锥体细胞似乎是膝状皮质、皮质-丘状和皮质-皮质投射的来源。在同一层中，终止于某一特定部位的细胞所占比例因层而异：显然，V层的所有大锥体都有终末位于上丘，VI层的锥体约有一半的终末位于外侧膝状核，而II层和III层的锥体仅有一小部分的终末位于单个皮质区域。观察了外侧膝状体A层和A1层不同类型细胞的皮质联系：投射到第17区的细胞数量明显多于投射到第18区的细胞，投射到皮质的细胞也从枕部、内侧板间核和后核投射到皮质。观察到几个中脑网状核与外侧膝状核有直接联系。最后发现上丘从未定带、丘脑网状核和腹侧膝状核发出的投射。
The projection of cells in different layers of several cortical visual areas in the cat were studied using the method of retrograde transport of horseradish peroxidase. Injections of the enzyme were made through a recording micropipette, making it possible to localize the injection site by physiological criteria. We found that layer VI cells projected to the lateral geniculate nucleus, while a distinct population of cells in layer V projected to the superior colliculus. Cells in layers II and III were the major sources of ipsilateral cortico‐cortical connections. This pattern of projection was consistent from one visual area to another. Pyramidal cells appeared to be the source of cortico‐geniculate, cortico‐collicular and cortico‐cortical projections. The proportion of cells within a layer that terminated in a given site varied from layer to layer: apparently all of the large pyramids in layer V had terminals in the superior colliculus, about half of the pyramids in layer VI had terminals in the lateral geniculate nucleus, while only a small proportion of the pyramids in layers II and III had terminals in any single cortical area. The results indicated a remarkable specificity in the projections of the cortical layers.The cortical connections of the different cell types in layers A and A1 of the lateral geniculate nucleus were also examined: the cells that projected to area 17 were much more numerous and were on the average smaller than those that projected to area 18. Projections to the cortex were also found from the pulvinar, the medial interlaminar nucleus and the posterior nucleus. Direct connections were observed to the lateral geniculate nucleus from several midbrain reticular nuclei. Finally, projections were found to the superior colliculus from the zona incerta, the reticular nucleus of the thalamus and the ventral lateral geniculate nucleus.