Synthesis of novel C2-symmetric chiral bis(oxazoline) ligands and their application in the enantioselective addition of diethylzinc to aldehydes
Synthesis of novel C2-symmetric chiral bis(oxazoline) ligands and their application in the enantioselective addition of diethylzinc to aldehydes
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新型C2对称手性双(恶唑啉)配体的合成及其在二乙基锌与醛对映选择性加成中的应用
DOI：
10.1016/j.tetasy.2003.11.006
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发表时间：
2004-01-12
影响因子：
--
通讯作者：
Wang, JB
中科院分区：
文献类型：
--
作者：
Fu, B;Du, DM;Wang, JB
合成了含二苯并[a，c]环庚二烯和二羟基的新型手性双(恶唑啉)配体，并研究了它们在二乙基锌与醛的不对称加成反应中的应用。芳香醛的对映体选择性普遍较高，可获得96%的ee。(C)2003爱思唯尔有限公司。保留所有权利。
Novel chiral bis(oxazoline) ligands bearing dibenzo[a,c]cycloheptadiene and a dihydroxy group have been synthesized and their application in the catalytic asymmetric addition of diethylzinc to aldehydes investigated. The enantioselectivities for the aromatic aldehydes are generally high and up to 96% ee was obtained. (C) 2003 Elsevier Ltd. All rights reserved.