A randomized study of raisins versus alternative snacks on glycemic control and other cardiovascular risk factors in patients with type 2 diabetes mellitus
A randomized study of raisins versus alternative snacks on glycemic control and other cardiovascular risk factors in patients with type 2 diabetes mellitus
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DOI：
10.1080/00913847.2015.998410
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发表时间：
2015-02-01
影响因子：
2.3
通讯作者：
Anderson, James
中科院分区：
文献类型：
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作者：
Bays, Harold;Weiter, Kathy;Anderson, James
正如体力活动的类型和持续时间可以对2型糖尿病（T2DM）患者的血糖水平和其他心脏代谢参数产生不同的影响一样，食物的类型也可以产生不同的影响。这项为期12周的随机研究对51名研究参与者进行了评估，评估了常规食用深色葡萄干与替代加工零食对T2DM患者血糖水平和其他心血管危险因素的影响。在这项研究中，与替代加工零食相比，食用葡萄干的人餐后血糖水平显著降低23%（P = 0.024）。同样与零食相比，食用葡萄干的人空腹血糖降低了19%，血红蛋白A1c降低了0.12%，尽管后者的发现没有达到统计学意义。关于血压，与替代加工零食相比，食用葡萄干的人收缩压显著降低8.7 mmHg（P = 0.035）（7.5% [P = 0.031]），但舒张压没有显著降低。与替代加工零食相比，食用葡萄干的人在体重，体重指数，腰围，空腹胰岛素，胰岛素抵抗的稳态模型评估，总胆固醇，低密度脂蛋白胆固醇，高密度脂蛋白胆固醇（HDL），甘油三酯或非HDL胆固醇水平方面没有显着改善。总的来说，这些数据支持葡萄干作为T2DM患者的健康替代品，而不是加工零食。
Just as the type and duration of physical activity can have variable effects on the glucose levels and other cardiometabolic parameters among patients with type 2 diabetes mellitus (T2DM), so can the types of foods have variable effects as well. This 12-week randomized study of 51 study participants evaluated the impact of routine consumption of dark raisins versus alternative processed snacks on glucose levels and other cardiovascular risk factors among patients with type T2DM. In this study, compared to alternative processed snacks, those who consumed raisins had a significant 23% reduction in postprandial glucose levels (P = 0.024). Also compared to snacks, those who consumed raisins had a 19% reduction in fasting glucose and 0.12% reduction in hemoglobin A1c, although these latter findings did not achieve statistical significance. Regarding blood pressure, compared to alternative processed snacks, those who consumed raisins had a significant 8.7 mmHg reduction in systolic blood pressure (P = 0.035) (7.5% [P = 0.031]) but did not experience a significant reduction in diastolic blood pressure. Compared to alternative processed snacks, those who consumed raisins did not have a significant improvement in body weight, body mass index, waist circumference, fasting insulin, homeostatic model assessment of insulin resistance, total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (HDL), triglyceride, or non-HDL cholesterol levels. Overall, these data support raisins as a healthy alternative compare to processed snacks in patients with T2DM.