Population- and individual-based approaches to the design and analysis of epidemiologic studies of sexually transmitted disease transmission.
Population- and individual-based approaches to the design and analysis of epidemiologic studies of sexually transmitted disease transmission.
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基于人群和个体的性传播疾病传播流行病学研究设计和分析方法。
DOI：
10.1093/infdis/174.supplement_2.s188
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发表时间：
1996
期刊：
影响因子：
--
通讯作者：
Padian,NS
中科院分区：
文献类型：
--
作者：
Shiboski,S;Padian,NS
性传播疾病（STD）传播的流行病学研究在设计和分析方面提出了一些独特的挑战。这些问题既源于性传播疾病传播的社会性质，也源于在收集关于接触和感染的准确和翔实数据方面固有的困难。获得性病的风险取决于个人因素和他人的行为和传染性。因此，为研究个人或群体的慢性病风险而开发的研究设计和分析方法可能不直接适用。性病传播的简单模型被用来调查这些问题，重点是如何个人和人口水平的因素之间的相互作用影响流行病学研究的设计和解释，特别注意解释的共同措施的关联和共同来源的偏见，在流行病学数据。可以修改现有的调查风险因素的方法，以便直接解决这些问题。
Epidemiologic studies of sexually transmitted disease (STD) transmission present a number of unique challenges in design and analysis. These arise both from the social nature of STD transmission and from inherent difficulties in collecting accurate and informative data on exposure and infection. Risk of acquiring an STD depends on both individual-level factors and the behavior and infectiousness of others. Consequently, study designs and analysis methods developed for studying chronic disease risk in individuals or groups may not apply directly. Simple models of STD transmission were used to investigate these issues, focusing on how the interplay between individual- and population- level factors influences design and interpretation of epidemiologic studies, with particular attention to interpretation of common measures of association and to common sources of bias in epidemiologic data. Existing methods for investigating risk factors can be modified such that these issues may be addressed directly.