Isolation and characterisation of intestinal spirochaetes.
Isolation and characterisation of intestinal spirochaetes.
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肠道螺旋体的分离和表征。
DOI：
10.1136/jcp.39.5.535
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发表时间：
1986
影响因子：
3.4
通讯作者：
A. West
中科院分区：
文献类型：
--
作者：
D. Tompkins;S. Foulkes;P. Godwin;A. West
通过在加入壮观霉素（400 mg/l）的血琼脂上进行厌氧培养，检查 1527 名受试者的粪便或直肠拭子是否存在肠道螺旋体。 23 份样本（1.5%）呈阳性，其中只有一份来自腹泻患者。所有阳性样本均来自亚洲人或已知的同性恋者。比较测试显示人类分离株和非致病性猪肠道螺旋体之间的表型非常相似。这些生物体与阿尔博短螺旋体不同，阿尔博吉短螺旋体是一种从组织学证实的肠道螺旋体病受试者中分离出来的螺旋体。
Faeces or rectal swabs from 1527 subjects were examined for the presence of intestinal spirochaetes by anaerobic culture on blood agar incorporating spectinomycin (400 mg/l). Twenty three specimens (1.5%) were positive, and only one of these came from a patient with diarrhoea. All positive specimens came from either Asians or known homosexuals. Comparative tests showed a close phenotypic similarity between the human isolates and non-pathogenic porcine intestinal spirochaetes. These organisms differ from Brachyspira aalborgi, a spirochaete isolated from subjects with histologically confirmed intestinal spirochaetosis.