Histomorphometric comparison of a biphasic bone ceramic to anorganic bovine bone for sinus augmentation: 6- to 8-month postsurgical assessment of vital bone formation. A pilot study.
Histomorphometric comparison of a biphasic bone ceramic to anorganic bovine bone for sinus augmentation: 6- to 8-month postsurgical assessment of vital bone formation. A pilot study.
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用于上窦增强的双相骨陶瓷与无机牛骨的组织形态测量比较：重要骨形成的 6 至 8 个月术后评估。
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
D. Tarnow
中科院分区：
文献类型：
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作者：
S. Froum;S. Wallace;Sang;N. Elian;D. Tarnow
这项盲法、随机、对照的试点研究首次从组织形态学上比较双相磷酸钙（BCP） （Straumann骨陶瓷）和无机牛骨基质（ABBM） （Bio-Oss）双侧窦移植术后6至8个月的重要骨形成。选取12例患者。在侧窦壁抬高后，一种材料被放置在右窦，另一种材料被放置在左窦，由随机化决定。移植后6 ~ 8个月（每个患者使用相同的时间框架），从移植区域取出一个环钻核并送去进行组织形态学分析。从12例患者21例愈合的鼻窦中取出核心。9例患者提供双侧核芯。10个BCP核和11个ABBM核的组织形态学分析显示，平均重要骨含量分别为28.35%和22.27%。BCP和ABBM的平均接枝颗粒残留量分别为28.4%和26.0%。BCP组与ABBM组双侧鼻窦重要骨形成差异无统计学意义（n = 9例，配对t检验）。组织学上，两种材料都具有骨导电性和支持新骨形成。未来的研究需要证实这种再生骨的能力来支持种植体的长期维护。
This blinded, randomized, controlled pilot investigation is the first to histomorphometrically compare vital bone formation following bilateral sinus grafting with a biphasic calcium phosphate (BCP) (Straumann Bone Ceramic) to an anorganic bovine bone matrix (ABBM) (Bio-Oss) 6 to 8 months following graft placement. Twelve patients were selected. Following elevation of the lateral sinus walls, one material was placed in the right sinus and the other material was placed in the left sinus, as determined by randomization. Six to 8 months after grafting (with the same time frame used for each patient), a trephine core was taken from the grafted area and sent for histomorphometric analysis. Cores were obtained from 21 healed sinuses in 12 patients. Nine patients provided bilateral cores. Histomorphometric analysis of 10 BCP cores and 11 ABBM cores revealed an average vital bone content of 28.35% and 22.27%, respectively. The average percentage of residual graft particles was 28.4% in the BCP cores and 26.0% in the ABBM cores. The difference in vital bone formation was not significantly different (n = 9 patients, paired t test) between bilateral sinuses treated with the BCP and those treated with the ABBM. Histologically, both materials appeared to be osteoconductive and support new bone formation. Future studies are needed to confirm the ability of this regenerated bone to support dental implant maintenance over time.
上颌窦抬高手术中人体矿化骨移植材料的组织学分析：病例系列。
DOI：
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发表时间：
2006
期刊：
The International journal of periodontics & restorative dentistry.
影响因子：
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作者：
Gapski,Ricardo;Neiva,Rodrigo;Oh,Tae-Ju;Wang,Hom-Lay
通讯作者：
Wang,Hom-Lay