Factors affecting degeneration in human temporomandibular joints as assessed histologically
Factors affecting degeneration in human temporomandibular joints as assessed histologically
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DOI：
10.1034/j.1600-0722.2002.11212.x
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发表时间：
2002-04-01
影响因子：
1.9
通讯作者：
Luder, HU
中科院分区：
文献类型：
--
作者：
Luder, HU
对15名女性和38名男性的尸体解剖标本进行了研究，以评估性别、年龄、牙齿缺失和关节盘位置对颞下颌关节（TMJ）退变的影响。将关节盘的位置分为正常和异常。对牙齿脱落进行计数和分类。对关节组织的退行性变化进行组织学评估和量化，同时考虑结构变化的严重程度及其沿关节面的沿着延伸。这在髁上单独记录。disc.和颞部，三个侧内侧关节区，以及假定的承重和非承重表面。重复测量的协方差分析用于检验影响因素。结果表明，性别和缺牙数的影响不显著，而年龄在55-60岁之间和牙弓长度的减少被证明是最重要的因素。负重似乎主要在年轻时起重要作用，椎间盘位置的影响也很显著。内紊乱合并牙弓长度缩短时，因此，颞下颌关节退行性变化的严重程度增加似乎主要与年龄增加有关。此外，它还可能取决于机械因素。特别是臼齿支撑丧失以及较小程度的盘位置异常。
The influence of sex, age, tooth loss, and articular disc position on temporomandiblular joint (TMJ) degeneration was evaluated in specimens collected at autopsy from 15 women and 38 men ranging in age from 15 to 92 yr. The position of the articular discs was classified as normal or abnormal. tooth loss was both counted and categorized. Degenerative changes of the articular tissues were assessed histologically and quantified, taking into account both the severity of structural alterations and their extension along the articular Surface. This was recorded separately in the condyle. disc. and temporal component, three latero-medial joint regions, and putative load-bearing and non-load-bearing Surfaces. Analysis of covariance with repeated measures served for testing contributing factors. It showed that the effects of sex and the number of missing teeth were insignificant, whereas age up to about 55-60 yr and reduction of dental arch length proved to be the most important factors. Load-bearing seemed to play a significant role mainly at younger ages, and the effect of disc position was significant. when internal derangement was combined with reduction of dental arch length. Thus, rising severity of TMJ degenerative changes appears to be associated primarily with increasing age. In addition, it may also depend on mechanical factors. in particular loss of molar support and, to a minor degree, abnormal disc position.