Homochirality and life
Homochirality and life
复制标题
DOI：
10.1002/tcr.20020
复制
发表时间：
2004-01-01
期刊：
影响因子：
6.6
通讯作者：
Saito, T
中科院分区：
文献类型：
--
作者：
Fujii, N;Saito, T
在生命出现之前，左手氨基酸（L-对映体）在原始地球上被选择，右手氨基酸（D-对映体）被淘汰。然而，随着分析方法的进步，最近在高级生物体中以游离氨基酸、肽和蛋白质的形式发现了D-氨基酸。游离D-氨基酸具有多种生理功能。含有D-氨基酸的动物肽是众所周知的阿片肽。蛋白质中的D-氨基酸与衰老有关。在这篇综述中，我们描述了在我们的身体中作为D-氨基酸生物系统存在和发挥作用的D-氨基酸。(C)2004年日本化学杂志论坛和Wiley Periodicals，Inc.
Before the emergence of life, left-handed amino acids (L-enantiomers) were selected and right-handed amino acids (D-enantiomers) were eliminated on the primal earth. Nevertheless, with the progress of analytical methods, D-amino acids have recently been found in higher order living organisms in the form of free amino acids, peptides, and proteins. Free D-amino acids have numerous physiological functions. D-amino acids containing animal pepticles are well known as opioid peptides. D-amino acids in protein are related to aging. In this review, we describe the D-amino acids that are present and function as D-amino acid biosystems in our bodies. (C) 2004 The Japan Chemical journal Forum and Wiley Periodicals, Inc.