Dynamics of red blood cells and vesicles in microchannels of oscillating width

Dynamics of red blood cells and vesicles in microchannels of oscillating width
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DOI:
10.1088/0953-8984/23/18/184116
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发表时间:
2011-05-11
影响因子:
2.7
通讯作者:
Franke, T.
Franke, T.
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Braunmueller, S.;Schmid, L.;Franke, T.

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我们研究了红细胞和流体脂质囊泡在周期性变化的微通道所产生的流体动力学流场中的动力学行为。对于红细胞,我们发现从具有振荡倾斜角和固定形状的制度过渡到具有振荡形状且流速增加的制度。我们已经确定交叉发生在临界比率L-y/v(m)近似为2.2 x 10(3)s,通道宽度L-y和红细胞速度v(m)。这些振荡叠加的形状过渡从一个盘状体的拖鞋形状在低速度和拖鞋降落伞过渡在高流速。
We have studied the dynamics of red blood cells and fluid lipid vesicles in hydrodynamic flow fields created by microchannels with periodically varying channel width. For red blood cells we find a transition from a regime with oscillating tilt angle and fixed shape to a regime with oscillating shape with increasing flow velocity. We have determined the crossover to occur at a critical ratio L-y/v(m) approximate to 2.2 x 10 (3) s with channel width L-y and red blood cell velocity v(m). These oscillations are superposed by shape transitions from a discocyte to a slipper shape at low velocities and a slipper to parachute transition at high flow velocities.