Event-related fMRI: Characterizing differential responses
Event-related fMRI: Characterizing differential responses
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DOI：
10.1006/nimg.1997.0306
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发表时间：
1998-01-01
期刊：
影响因子：
5.7
通讯作者：
Turner, R
中科院分区：
文献类型：
--
作者：
Friston, KJ;Fletcher, P;Turner, R
我们提出了一种方法来表征事件相关的血流动力学反应之间的差异，在功能性磁共振成像，由不同种类的刺激引起的。这种方法是基于线性卷积模型和统计参数映射所采用的标准推断统计。特别是，我们模型诱发反应，和他们的差异，在基函数的刺激时间。这有助于表征相对于重复时间具有高有效时间分辨率的时间响应分布。为了证明这项技术，我们研究了不同的反应，视觉呈现的话，已经看到之前扫描或新颖。这些差异的形式涉及反应成分的幅度和潜伏期。在本文中，我们专注于双边腹外侧前额叶反应，表现出失活以前看到的话和激活的新的话。(C)北京：科学出版社.
We present an approach to characterizing the differences among event-related hemodynamic responses in functional magnetic resonance imaging that are evoked by different sorts of stimuli. This approach is predicated on a linear convolution model and standard inferential statistics as employed by statistical parametric mapping. In particular we model evoked responses, and their differences, in terms of basis functions of the peri-stimulus time. This facilitates a characterization of the temporal response profiles that has a high effective temporal resolution relative to the repetition time. To demonstrate the technique we examined differential responses to visually presented words that had been seen prior to scanning or that were novel. The form of these differences involved both the magnitude and the latency of the response components. In this paper we focus on bilateral ventrolateral prefrontal responses that show deactivations for previously seen words and activations for novel words. (C) 1998 Academic Press.