Trastuzumab (Herceptin)

Trastuzumab (Herceptin)
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DOI:
10.3174/ajnr.a2619
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发表时间:
2011-09-01
影响因子:
3.5
通讯作者:
Mukherji, S. K.
Mukherji, S. K.
中科院分区:
医学2区
文献类型:
--
作者:
Gemmete, J. J.;Mukherji, S. K.

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赫赛汀(曲妥珠单抗)是一种干扰HER2受体的人单克隆抗体。它是目前唯一一种FDA批准的HER2阳性乳腺癌治疗抗体。本文将介绍这种单克隆抗体的作用机制以及临床作用。
Herceptin (trastuzumab) is a human monoclonal antibody that interferes with the HER2 receptor. It is currently the only FDA-approved therapeutic antibody for HER2-positive breast cancer. This article will present the mechanism at action as well as the clinical role at this monoclonal antibody.