Antibiotics with ansa rings
Antibiotics with ansa rings
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DOI：
10.1021/ar50050a003
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发表时间：
1972-02
影响因子：
18.3
通讯作者：
J. Rinehart
中科院分区：
文献类型：
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作者：
J. Rinehart
通常，当一种新结构类型的抗生素出现在化疗现场时，很快就会有相同类型的其他代表加入，因此人们可以开始谈论一类抗生素。这是一类含有脂肪族柄桥的新型抗生素的情况，1所述脂肪族柄桥是连接芳香核的两个不相邻位置的桥，
Often when an antibiotic of a new structural type appears on the chemotherapeutic scene it is soon joined by additional representatives of the same type, so that one can begin to speak of a class of antibiotics. This is the case with a new class of antibiotics con-taining an aliphatic ansa bridge, 1 a bridge connecting two nonadjacent positions of an aromatic nucleus, for which the term “ansamycins” has been suggested by