Oscillatory changes related to the forced termination of a movement
Oscillatory changes related to the forced termination of a movement
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DOI：
10.1016/j.clinph.2007.10.017
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发表时间：
2008-02-01
影响因子：
4.7
通讯作者：
Artieda, J.
中科院分区：
文献类型：
--
作者：
Alegre, M.;Alvarez-Gerriko, I.;Artieda, J.
目的：刺激诱导的运动伴随着一定的振荡变化模式，包括额叶15 Hz同步化、中枢运动周围去兴奋化和运动后对侧β反弹。我们的目的是研究一个单一的复杂的运动程序（签名）的强制终止相关的振荡变化，并将它们与正常终止后观察到的motion.Methods：五十八个参考的EEG通道进行了分析，在10名健康受试者。2000 Hz音调（S1，go信号）指示受试者开始书写他/她的完整签名。0.8 s后的第二个2000 Hz音调（50%概率：S2，停止信号）指示受试者立即停止。运动相关的能量变化进行了评估，通过时间-频率（Gabor）transforms.Results：一个正面的15 Hz的同步后，观察到S1，但不是后S2。运动后β增加的幅度显着降低时，运动异常终止（p = 0.005），而运动前后减少是similar.Conclusions：强制终止的运动程序显着降低幅度的运动后β增量，保存其时间模式。此外，存在的15 Hz的额叶同步后，只有SI，连同以前的研究结果，表明，在去/不去和停止signals.Significance：我们的研究结果表明，参与的额叶机制是非常不同的β反弹是一个积极的过程，独立的围运动β下降，这是如何运动终止的影响。(c)2007年国际临床神经生理学联合会。由Elsevier爱尔兰有限公司出版。保留所有权利。
Objective: Stimulus-induced movements are accompanied by a definite pattern of oscillatory changes, that include a frontal 15 Hz synchronization, a central peri-movement desynchronization, and a contralateral beta rebound after the movement. Our aim was to study the oscillatory changes related to the forced termination of a single complex motor program (signature) and compare them with those observed after the normal termination of the movement.Methods: Fifty-eight reference-free EEG channels were analyzed in 10 healthy subjects. A 2000 Hz tone (S1, go signal) indicated the subject to begin to write his/her complete signature. A second 2000 Hz tone 0.8 s afterwards (50% probability: S2, stop signal) indicated the subject to stop immediately. Movement-related energy changes were evaluated by means of time-frequency (Gabor) transforms.Results: A frontal 15 Hz synchronization was observed after S1, but not after S2. The amplitude of the post-movement beta increase was significantly lower when the movement was abnormally terminated (p = 0.005), while the peri-movement decrease was similar.Conclusions: The forced termination of a motor program reduces significantly the amplitude of the post-movement beta increment, conserving its temporal pattern. Also, the presence of the 15 Hz frontal synchronization only after SI, together with the results of previous studies, suggests that the frontal mechanisms involved in go/no go and stop signals are very different.Significance: Our results indicate that the beta rebound is an active process, independent of the peri-movement beta decrease, which is influenced by how the movement is terminated. (c) 2007 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.