Four-dimensional single breathhold magnetic resonance imaging using kt-BLAST enables reliable assessment of left- and right-ventricular volumes and mass
Four-dimensional single breathhold magnetic resonance imaging using kt-BLAST enables reliable assessment of left- and right-ventricular volumes and mass
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DOI：
10.1002/jmri.20877
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发表时间：
2007-04-01
影响因子：
4.4
通讯作者：
Paetsch, Ingo
中科院分区：
文献类型：
--
作者：
Jahnke, Cosima;Nagel, Eike;Paetsch, Ingo
目的：与标准多次屏气电影成像相比，前瞻性地确定四维 (4D) kt 广泛使用线性采集加速技术 (BLAST) 加速 MRI (kt-BLAST) 用于评估左心室 (LV) 体积和质量以及右心室 (RV) 体积的准确性。 材料和方法：总共 40 名疑似或已知冠状动脉疾病 (CAD) 的患者接受了心脏 MRI。对每位患者执行标准多层电影稳态自由进动 (SSFP) 序列，在多次屏气期间完全覆盖心室。此外，在一次屏气期间获得了具有完整心室覆盖的 kt-BLAST 加速 4D 序列。为了比较 SSFP 和 kt-BLAST，确定了以下 LV 参数：舒张末期和收缩末期容积、射血分数、舒张末期直径和质量。为了比较 RV 尺寸，评估了舒张末期和收缩末期容积以及射血分数。结果：左心室容积、射血分数、直径和质量显示 SSFP 和 kt-BLAST 之间存在很强的相关性（r = 0.98-0.99；P < 0.01）。此外，RV 参数表现出高度相关性（r = 0.97-0.98；P < 0.01）。对于所有参数，两种方法之间的计算偏差很小 (0.4-4%)。结论：与标准多层、多次屏气 SSFP 成像相比，4D kt-BLAST 加速 MRI 能够在一次屏气期间准确评估 LV 和 RV 定量参数。
Purpose: To prospectively determine the accuracy of four-dimensional (4D) kt-broad-use linear acquisition speed-up technique (BLAST) accelerated MRI (kt-BLAST) for the assessment of left-ventricular (LV) volumes and mass as well as right-ventricular (RV) volumes in comparison to standard multiple breathhold cine imaging.Materials and Methods: A total of 40 patients with suspected or known coronary artery disease (CAD) underwent cardiac MRI. In each patient a standard multislice cine steady-state free precession (SSFP) sequence was performed with complete ventricular coverage during multiple breathholds. Additionally, a kt-BLAST-accelerated 4D sequence with complete ventricular coverage was acquired during one single breathhold. For comparison of SSFP and kt-BLAST, the following LV parameters were determined: end-diastolic and end-systolic volumes, ejection fraction, end-diastolic diameter and mass. For comparison of RV dimensions, end-diastolic and end-systolic volumes and ejection fraction were assessed.Results: LV volumes, ejection fraction, diameter, and mass showed a strong correlation between SSFP and kt-BLAST (r = 0.98-0.99; P < 0.01). In addition, RV parameters demonstrated a high correlation (r = 0.97-0.98; P < 0.01). For all parameters, the calculated bias between both methods was found to be minimal (0.4-4%).Conclusion: 4D kt-BLAST-accelerated MRI enabled the accurate assessment of LV and RV quantitative parameters during one single breathhold when compared to standard multislice, multiple breathhold SSFP imaging.