Cochlear Implant Research and Development in the Twenty-first Century: A Critical Update.

Cochlear Implant Research and Development in the Twenty-first Century: A Critical Update.
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DOI:
10.1007/s10162-021-00811-5
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发表时间:
2021-10
期刊:
Journal of the Association for Research in Otolaryngology : JARO
影响因子:
--
通讯作者:
Goehring T
Goehring T
中科院分区:
其他
文献类型:
--
作者:
Carlyon RP;Goehring T

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人工耳蜗是世界上最成功的感觉假肢,近几十年来一直是研究和发展的热点。我们批判性地回顾了从世纪之交到现在,CI研究的进展及其在改善患者预后方面的成功。这篇综述的重点是处理、刺激和听力学方法,这些方法已经被用来试图提高人类CI听众的语音感知,以及听觉系统对电刺激的反应的基本新见解。定向麦克风和新的降噪和预处理算法的引入已经产生了强大的,有时是实质性的改进。新的语音处理算法,电流聚焦方法的使用,以及个性化(逐个患者)电极亚组的失活已经产生了更适度的改善。我们认为,已经取得并将继续取得渐进式的进展,这些进展可能会大大改善患者的预后,但每项进展的适度规模将需要更多地关注实验设计和功率。我们还简要讨论了目前正在动物模型中开发的有前途的技术的潜力和局限性,并为研究人员提出了在广泛的听力情况下最大限度地发挥CIs潜力以改善听力的策略。
Cochlear implants (CIs) are the world’s most successful sensory prosthesis and have been the subject of intense research and development in recent decades. We critically review the progress in CI research, and its success in improving patient outcomes, from the turn of the century to the present day. The review focuses on the processing, stimulation, and audiological methods that have been used to try to improve speech perception by human CI listeners, and on fundamental new insights in the response of the auditory system to electrical stimulation. The introduction of directional microphones and of new noise reduction and pre-processing algorithms has produced robust and sometimes substantial improvements. Novel speech-processing algorithms, the use of current-focusing methods, and individualised (patient-by-patient) deactivation of subsets of electrodes have produced more modest improvements. We argue that incremental advances have and will continue to be made, that collectively these may substantially improve patient outcomes, but that the modest size of each individual advance will require greater attention to experimental design and power. We also briefly discuss the potential and limitations of promising technologies that are currently being developed in animal models, and suggest strategies for researchers to collectively maximise the potential of CIs to improve hearing in a wide range of listening situations.
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影响因子: 2.4
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影响因子: --
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