Evolution of oncogenes: From c-abl to v-abl
Evolution of oncogenes: From c-abl to v-abl
复制标题
癌基因的进化：从c-abl到v-abl
作者：
J. Y. Wang
逆转录病毒的致癌基因来源于细胞基因，这一发现导致人们开始寻找病毒基因与其细胞对应基因之间的差异，以解释前者的致癌活性。两种致癌基因，abl和src基因，最近受到了这样的审查。src基因将是后面文章的主题：在这里，Jean Yin Jen Wang讨论了abl基因。
The discovery that the oncogenes of retroviruses are derived from cellular genes has led to a search for differences between the viral gene and its cellular counterpart that might explain the oncogenic activity of the former. Two oncogenes, the abl and the src genes, have recently come under such scrutiny. The src gene will be the subject of a later article: here, Jean Yin Jen Wang discusses the abl gene.