Involution of infantile haemangiomas after imiquimod 5% cream
Involution of infantile haemangiomas after imiquimod 5% cream
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DOI：
10.1111/j.1365-2230.2007.02676.x
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发表时间：
2008-07-01
影响因子：
4.1
通讯作者：
Cook, L. J.
中科院分区：
文献类型：
--
作者：
Barry, R. B. M.;Hughes, B. R.;Cook, L. J.
婴儿血管瘤是一种常见的儿童疾病，通常会自行解决，并期待管理。在一小部分复杂病例中，血管瘤可能伴有并发症，如持续出血、溃疡、进食困难或视力受损。在这种情况下，积极治疗往往是必要的。目前的干预措施包括手术、激光和免疫调节治疗。5%咪喹莫特乳膏是一种新的替代局部治疗，可能在这些患者的管理中发挥潜在作用。我们介绍了我们的经验咪喹莫特5%霜治疗五个儿童难以血管瘤。我们讨论了它的疗效和可能遇到的一些副作用，这是以前没有报道过的。
Infantile haemangioma is a common childhood condition, which usually resolves spontaneously and is managed expectantly. In a small percentage of complex cases, haemangiomas may be associated with complications such as persistent bleeding, ulceration, feeding difficulties or visual impairment. Active treatment is often necessary in such cases. Current interventions include surgical, laser and immunomodulatory treatments. Imiquimod 5% cream is a novel alternative topical treatment that may have a potential role in management of these patients. We present our experience of imiquimod 5% cream in the treatment of five children with difficult haemangiomas. We discuss its efficacy and some of the side effects that may be encountered, which have not previously been reported.