Repeat Revascularization After Contemporary Percutaneous Coronary Intervention An Evaluation of Staged, Target Lesion, and Other Unplanned Revascularization Procedures During the First Year
Repeat Revascularization After Contemporary Percutaneous Coronary Intervention An Evaluation of Staged, Target Lesion, and Other Unplanned Revascularization Procedures During the First Year
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DOI：
10.1161/circinterventions.111.967802
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发表时间：
2012-12-01
影响因子：
5.6
通讯作者：
Kleiman, Neal S.
中科院分区：
文献类型：
--
作者：
Stolker, Joshua M.;Cohen, David J.;Kleiman, Neal S.
背景-尽管药物洗脱支架和强化二级预防有助于改善经皮冠状动脉介入治疗（PCI）后的结局，但重复血运重建在当代实践中仍然相对常见。我们使用来自药物洗脱支架和缺血事件注册中心的多中心评价数据，评价在当代PCI术后第一年内分期血运重建、靶病变血运重建（TLR）和其他非靶血运重建的相对频率和时间。和其他计划外手术（靶血管或其他冠状动脉中的其他部位）在时间依赖性模型中使用Kaplan-Meier寿命表估计进行评价。使用逻辑回归确定TLR和非靶部位计划外血运重建的预测因素。2004年7月至2007年6月，在美国55家医院招募了10144例接受PCI的患者，其中86%接受了至少1种药物洗脱支架治疗。12%的患者在第一年内需要重复血运重建（3%分期; 9%计划外）。超过75%的分期血运重建得到实施
Background-Although drug-eluting stents and intensive secondary prevention have contributed to improved outcomes after percutaneous coronary intervention (PCI), repeat revascularization remains relatively common in contemporary practice. We used data from the multicenter Evaluation of Drug-Eluting Stents and Ischemic Events registry to evaluate the relative frequency and timing of staged revascularization, target lesion revascularization (TLR), and other nontarget revascularization during the first year after contemporary PCI.Methods and Results-Patients with staged revascularization, TLR, and other unplanned procedures (elsewhere in the target vessel or in other coronary arteries) were evaluated in time-dependent models using Kaplan-Meier life-table estimation. Predictors of TLR and unplanned revascularization at nontarget sites were identified using logistic regression. Between July 2004 to June 2007, 10 144 patients undergoing PCI were enrolled at 55 US hospitals, of whom 86% were treated with at least 1 drug-eluting stent. Twelve percent required repeat revascularization within the first year (3% staged; 9% unplanned). More than 75% of staged revascularizations were performed