Coronary computed tomography angiography using ultra-low-dose contrast media: radiation dose and image quality
Coronary computed tomography angiography using ultra-low-dose contrast media: radiation dose and image quality
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DOI：
10.1007/s10554-013-0201-2
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发表时间：
2013-08-01
影响因子：
2.1
通讯作者：
Kodama, Kazuhisa
中科院分区：
文献类型：
--
作者：
Komatsu, Sei;Kamata, Teruaki;Kodama, Kazuhisa
分析80 kV冠状动脉CT血管造影（CCTA）的侵入性和图像质量。我们招募了 181 名低体重和低钙水平的患者。其中，154 名患者被随机分配到 3 组中的一组：280 HU/80 kV (n = 51)； 350 HU/80 kV（n = 51）；或 350 HU/120 kV (n = 52)。造影剂（CM）的量由CT数字控制系统决定。 27 名患者因定时推注的时间密度曲线无效而被排除。测量CM预测量、体积CT剂量指数、剂量长度乘积、有效剂量、图像噪声和5点图像质量。 80 kV/280 HU、80 kV/350 HU 和 120 kV/350 HU 组的 CM 量分别为 10 +/- A 4 mL、15 +/- A 7 mL 和 30 +/- A 6 mL。尽管 80 kV 时的图像噪声大于 120 kV，但 80 kV/350 HU 和 120 kV/350 HU 之间的图像质量没有显着差异 (p = 0.390)。 80 kV/280 HU 和 80 kV/350 HU 之间的图像质量没有显着差异（4.4 +/- A 0.7 与 4.7 +/- A 0.4，p = 0.056）。 80 kV CCTA 的 CM 量和有效剂量低于 120 kV CCTA。 80 kV/280 HU 的 CCTA 可以减少必要的 CM 量和辐射剂量，同时保持图像质量。
To analyze the invasiveness and image quality of coronary CT angiography (CCTA) with 80 kV. We enrolled 181 patients with low body weight and low calcium level. Of these, 154 patients were randomly assigned to 1 of 3 groups: 280 HU/80 kV (n = 51); 350 HU/80 kV (n = 51); or 350 HU/120 kV (n = 52). The amount of contrast media (CM) was decided with a CT number-controlling system. Twenty-seven patients were excluded because of an invalid time density curve by timing bolus. The predicted amount of CM, volume CT dose index, dose-length product, effective dose, image noise, and 5-point image quality were measured. The amounts of CM for the 80 kV/280 HU, 80 kV/350 HU, and 120 kV/350 HU groups were 10 +/- A 4 mL, 15 +/- A 7 mL, and 30 +/- A 6 mL, respectively. Although image noise was greater at 80 than 120 kV, there was no significant difference in image quality between 80 kV/350 HU and 120 kV/350 HU (p = 0.390). There was no significant difference in image quality between 80 kV/280 HU and 80 kV/350 HU (4.4 +/- A 0.7 vs. 4.7 +/- A 0.4, p = 0.056). The amount of CM and effective dose was lower for 80 kV CCTA than for 120 kV CCTA. CCTA at 80 kV/280 HU may decrease the amount of CM and radiation dose necessary while maintaining image quality.