Early post-infarction angina. Ischemia at a distance and ischemia in the infarct zone.
Early post-infarction angina. Ischemia at a distance and ischemia in the infarct zone.
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梗塞后早期心绞痛。
DOI：
10.1056/nejm198111053051901
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发表时间：
1981
期刊：
影响因子：
--
通讯作者：
Bulkley,BH
中科院分区：
文献类型：
--
作者：
Schuster,EH;Bulkley,BH
我们研究了两种形式的梗死后心绞痛：远距离缺血（心绞痛与新的心电图变化远离急性梗死）和梗死区缺血（心绞痛与新的心电图变化限于最初涉及的急性梗死的导线）。70例早期梗死后心绞痛患者平均随访6个月; 43例远处缺血，27例梗死区缺血。整个组的死亡率为56%，但在远距离缺血的患者中死亡率为72%（43例患者中的31例），在梗死区缺血的患者中死亡率为33%（27例患者中的9例）（P<0.005）。梗死后心绞痛患者死亡率高;在这些患者中，远距离缺血可能代表大面积存活但受损心肌的患者中的一个特别高风险的亚组，这些患者可以从积极的干预中获益。（《新英格兰医学杂志》1981年; 305：1101-5）
We studied two forms of post-infarction angina: ischemia at a distance (angina with new electrocardiographic changes distant from the acute infarct) and ischemia in the infarct zone (angina with new electrocardiographic changes limited to the leads originally involved by the acute infarct). Seventy patients with early post-infarction angina were followed for an average of six months; 43 had ischemia at a distance, and 27 had ischemia in the infarct zone. Mortality in the entire group was 56 per cent, but it was 72 per cent (31 of 43 patients) among those with ischemia at a distance and 33 per cent (nine of 27) among those with ischemia in the infarct zone (P<0.005). Post-infarction angina identifies patients with high mortality; among such patients, ischemia at a distance may represent an especially high-risk subset of patients with large areas of viable but jeopardized myocardium who could benefit from aggressive intervention. (N Engl J Med. 1981; 305:1101–5.)