Loss of human photoreceptor sensitivity associated with chronic exposure to ultraviolet radiation.
Loss of human photoreceptor sensitivity associated with chronic exposure to ultraviolet radiation.
复制标题
人类光感受器敏感性的丧失与长期暴露于紫外线辐射有关。
DOI：
10.1016/s0161-6420(89)32693-5
复制
发表时间：
1989
期刊：
影响因子：
13.7
通讯作者：
Pfoff,DS
中科院分区：
文献类型：
--
作者：
Werner,JS;Steele,VG;Pfoff,DS
人眼的晶状体透镜吸收大部分入射紫外线辐射（UVR），但是当透镜被移除时，这种辐射可以到达光感受器。通过对接受双侧白内障摘除和人工晶状体（IOL）植入的患者进行心理物理测量，确定UVR暴露对视锥细胞感受器敏感性的影响。植入一只眼睛的IOL含有吸收入射UVR的发色团，而植入另一只眼睛的IOL则透射UVR。五年的暴露于环境紫外线与选择性损失的敏感性的短波锥光感受器。这些结果与长期暴露于UVR可能损害人视网膜的假设一致。
The crystalline lens of the human eye absorbs most of the incident ultraviolet radiation (UVR), but when the lens is removed, this radiation can reach the photoreceptors. The consequences of UVR exposure on cone receptor sensitivity were determined from psychophysical measurements in patients who had undergone bilateral cataract extraction and implantation of intraocular lenses (IOLs). The IOL implanted in one eye contained chromophores that absorb incident UVR, whereas that implanted in the other eye transmitted UVR. Five years of exposure to ambient UVR was associated with a selective loss in sensitivity of the short-wave cone photoreceptors. These results are consistent with the hypothesis that chronic exposure to UVR may damage the human retina.