Exposure to inorganic arsenic in drinking water and total urinary arsenic concentration in a Chilean population
Exposure to inorganic arsenic in drinking water and total urinary arsenic concentration in a Chilean population
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DOI：
10.1016/j.envres.2005.02.007
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发表时间：
2005-06-01
影响因子：
8.3
通讯作者：
Loomis, D
中科院分区：
文献类型：
--
作者：
Caceres, DD;Pino, P;Loomis, D
在智利三个主要城市（安托法加斯塔、圣地亚哥和特木科）进行的一项横断面研究中，评价了非职业暴露人群通过饮用水接触无机砷与尿砷排泄量的关系。三个人群阶层（老年人、学生和工人）共756人在暴露后第二天提供了第一次晨尿标本，并进行了食物调查。通过分析自来水样本，加上24小时饮食回忆和食物频率问卷，估计饮用水中的砷摄入量。多水平分析用于评估经预测变量调整的年龄组和城市因素的影响。安托法加斯塔饮用水和尿液中的砷含量明显高于其他城市。城市和个人水平的因素，12%和88%，分别占尿砷浓度的变异。尿砷浓度的主要预测因素是饮水总砷摄入量和年龄。这些研究结果表明，饮用水中的砷浓度仍然是智利人口接触无机砷的主要因素。(c)2005年爱思唯尔公司All rights reserved.
The relationship of inorganic arsenic exposure through drinking water and total urinary arsenic excretion in a nonoccupationally exposed population was evaluated in a cross-sectional study in three mayor cities of Chile (Antofagasta, Santiago, and Temuco). A total of 756 individuals in three population strata (elderly, students, and workers) provided first morning void urine specimens the day after exposure and food surveys were administered. Arsenic intake from drinking water was estimated from analysis of tap water samples, plus 24-h dietary recall and food frequency questionnaires. Multilevel analysis was used to evaluate the effects of the age group and city factors adjusted by predictor variables. Arsenic levels in drinking water and urine were significantly higher in Antofagasta compared with the other cities. City-and individual-level factors, 12% and 88%, respectively, accounted for the variability in urinary arsenic concentration. The main predictors of urinary arsenic concentration were total arsenic Consumption through water and age. These findings indicate that arsenic concentration in drinking water continues to be the principal contributing factor to exposure to inorganic arsenic in the Chilean population. (c) 2005 Elsevier Inc. All rights reserved.