Can allogeneic haematopoietic cell transplantation be curative in classical Crohn's disease?
Can allogeneic haematopoietic cell transplantation be curative in classical Crohn's disease?
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同种异体造血细胞移植可以治愈经典克罗恩病吗？
DOI：
10.1111/bjh.18551
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发表时间：
2023
影响因子：
6.5
通讯作者：
Verneris,MichaelR
中科院分区：
文献类型：
--
作者：
McLaughlin,Laura;DeZoeten,Edwin;Verneris,MichaelR
Moser等人的文章详细介绍了11例免疫缺陷综合征的主要表现为炎症性肠病（IBD）的患者接受同种异体移植治疗的结局。作者报告了并发症（包括移植物抗宿主病）和症状消退的低发生率。在这里，我们概述了同种异体移植是否应该更广泛地考虑IBD。评论：Moser et al. Treatment of inborn errors of immunity patients with inflammatory bowel disease phenotype by allogeneic stem cell transplantation.Br J Haematol 2023;200：595 - 607.
The article by Moser et al. details the outcomes of 11 patients with inflammatory bowel disease (IBD) as the main manifestation of their immune deficiency syndrome who are treated with allogeneic transplantation. The authors report low rates of complications (including graft‐versus‐host disease) and resolution of symptoms. Here we outline whether allogeneic transplantation should be considered more broadly for IBD.Commentary on: Moser et al. Treatment of inborn errors of immunity patients with inflammatory bowel disease phenotype by allogeneic stem cell transplantation.Br J Haematol2023;200:595‐607.