Bodily pain in survivors of acute respiratory distress syndrome: A 1-year longitudinal follow-up study.
Bodily pain in survivors of acute respiratory distress syndrome: A 1-year longitudinal follow-up study.
复制标题
急性呼吸窘迫综合征幸存者的身体疼痛：一项为期一年的纵向随访研究。
DOI：
10.1016/j.jpsychores.2021.110418
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发表时间：
2021
影响因子：
4.7
通讯作者：
Neufeld,KarinJ
中科院分区：
文献类型：
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作者：
Probert,JuliaM;Lin,Shihong;Yan,Haijuan;Leoutsakos,Jeannie-MarieS;Dinglas,VictorD;Hosey,MeganM;Parker,AnnM;Hopkins,RamonaO;Needham,DaleM;Neufeld,KarinJ
急性呼吸窘迫综合征（ARDS）幸存者在重症监护室后的恢复过程中经常会经历身体疼痛。纵向过程，危险因素和协会与身体和神经心理健康是lacked.MethodsWe收集自我报告的疼痛使用简表-36身体疼痛（SF-36 BP）量表，按性别和年龄标准化（范围：0-100;更高的分数=更少的疼痛），沿着多中心的身体和精神健康测量，在6个月和12个月随访时，826名ARDS幸存者的前瞻性队列。我们通过单独的未经调整的回归models.ResultsPain患病率（SF-36 BP ≤40）分别为45%和42%，在6个月和12个月的基线和ICU变量的关联。在有6个月和12个月数据的706例患者中，34%在两个时间点报告疼痛。ARDS前就业与6个月（平均差（标准误），5.7（0.9），p< 0.001）和12个月（6.3（0.9），p< 0.001）的疼痛较轻相关;吸烟史与更大的疼痛相关（分别为-5.0（0.9），p< 0.001和-5.4（1.0），p< 0.001）。在ICU使用阿片类药物与更大的疼痛相关（分别为-6.3（2.7），p= 0.02和-7.3（2.8），p= 0.01）。在6个月，174例（22%）患者报告共发生的疼痛，抑郁和焦虑，227（33%）报告共发生的疼痛和受损的身体function. Conclusionalnearly一半的ARDS幸存者报告身体疼痛，在6个月和12个月的随访，三分之一的报告疼痛在这两个时间点。ARDS前失业、吸烟史和ICU中阿片类药物使用可能会识别出在恢复期间报告更大疼痛的患者。鉴于其频繁的共同发生，临床医生应该管理身体和神经心理问题时，疼痛的报告。
PurposeAcute respiratory distress syndrome (ARDS) survivors frequently experience bodily pain during recovery after the intensive care unit. Longitudinal course, risk factors and associations with physical and neuropsychological health is lacking.MethodsWe collected self-reported pain using the Short Form-36 Bodily Pain (SF-36 BP) scale, normalized for sex and age (range: 0–100; higher score = less pain), along with physical and mental health measures in a multi-center, prospective cohort of 826 ARDS survivors at 6- and 12-month follow-up. We examined baseline and ICU variables' associations with pain via separate unadjusted regression models.ResultsPain prevalence (SF-36 BP ≤40) was 45% and 42% at 6 and 12 months, respectively. Among 706 patients with both 6- and 12-month data, 34% reported pain at both timepoints. Pre-ARDS employment was associated with less pain at 6-months (mean difference (standard error), 5.7 (0.9),p< 0.001) and 12-months (6.3 (0.9),p< 0.001); smoking history was associated with greater pain (−5.0 (0.9),p< 0.001, and − 5.4 (1.0),p< 0.001, respectively). In-ICU opioid use was associated with greater pain (−6.3 (2.7),p= 0.02, and − 7.3 (2.8),p= 0.01, respectively). At 6 months, 174 (22%) patients reported co-occurring pain, depression and anxiety, and 227 (33%) reported co-occurring pain and impaired physical function.ConclusionNearly half of ARDS survivors reported bodily pain at 6- and 12-month follow-up; one-third reported pain at both time points. Pre-ARDS unemployment, smoking history, and in-ICU opioid use may identify patients who report greater pain during recovery. Given its frequent co-occurrence, clinicians should manage both physical and neuropsychological issues when pain is reported.