Preparation and antibacterial activity of electrospun chitosan/poly(ethylene oxide) membranes containing silver nanoparticles
Preparation and antibacterial activity of electrospun chitosan/poly(ethylene oxide) membranes containing silver nanoparticles
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DOI：
10.1007/s00396-009-2108-y
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发表时间：
2009-12-01
影响因子：
2.4
通讯作者：
Yuan, Xiaoyan
中科院分区：
文献类型：
--
作者：
An, Jing;Zhang, Hong;Yuan, Xiaoyan
通过静电纺丝含Ag/CS胶体的CS/PEO溶液，通过Ag离子的原位化学还原，成功制备了相当均匀的含银纳米粒子（AgNPs）的壳聚糖（CS）/聚环氧乙烷（PEO）超细纤维。 X 射线衍射图证实了电纺超细纤维中存在 AgNP。透射电镜下观察到AgNPs均匀分布在CS/PEO超细纤维中，尺寸小于5 nm。 X射线光电子能谱表明复合超细纤维中AgaEuro中心点O键的存在导致Ag和CS之间紧密结合。电纺Ag/CS/PEO纤维膜对大肠杆菌的抗菌活性评价表明，超细纤维中的AgNPs显着增强了对细菌的灭活作用。
Fairly uniform chitosan (CS)/poly(ethylene oxide) (PEO) ultrafine fibers containing silver nanoparticles (AgNPs) were successfully prepared by electrospinning of CS/PEO solutions containing Ag/CS colloids by means of in situ chemical reduction of Ag ions. The presence of AgNPs in the electrospun ultrafine fibers was confirmed by X-ray diffraction patterns. The AgNPs were evenly distributed in CS/PEO ultrafine fibers with the size less than 5 nm observed under a transmission electron microscope. X-ray photoelectron spectroscopy suggested that the existence of AgaEuro center dot O bond in the composite ultrafine fibers led to the tight combination between Ag and CS. Evaluation of antimicrobial activities of the electrospun Ag/CS/PEO fibrous membranes against Escherichia coli showed that the AgNPs in the ultrafine fibers significantly enhanced the inactivation of bacteria.