INSULIN-RESPONSE TO A SHORT STRESS PERIOD
INSULIN-RESPONSE TO A SHORT STRESS PERIOD
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DOI：
10.1016/0306-4530(89)90022-x
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发表时间：
1989-01-01
影响因子：
3.7
通讯作者：
EZCURRA, E
中科院分区：
文献类型：
--
作者：
ALVAREZ, MA;PORTILLA, L;EZCURRA, E
在24名健康志愿者中(7名女性，17名男性；平均年龄23。+-)。5年)，我们研究了社会压力下认知冲突引起的30分钟短应激期的胰岛素反应。应激期前后分别测定胰岛素、生长激素(GH)、血糖和血压。应激期后胰岛素水平显著升高(p=0.02，配对t检验)。以胰岛素差值为因变量，初始生长激素和血糖水平及其增量和体重指数为预测因素的多元逐步回归分析表明，胰岛素水平的变化不受任何预测因素的影响。我们讨论了自主神经支配对胰岛素分泌的影响以及应激过程中胰岛素敏感性的可能变化。
In 24 healthy volunteers (seven women, 17 men; mean age 23 .+-. 5 years), we studied the insulin response to a short stress period of 30 min, induced by cognitive conflict under social pressure. Insulin, growth hormone (GH), blood glucose and blood pressure (BP) determinations were performed before and after the stress period. There was a significant increase in insulin levels following the stress period (p = 0.02, paired t-test). A multiple stepwise regression analysis, with insulin difference as the dependent variable and initial GH and blood sugar levels, their increments and body mass index as predictors, showed that insulin variation was independent of any of the predictors. We discuss the influence of autonomic innervation on insulin secretion and the possible change in insulin sensitivity during stress.