Sensitivity and specificity of the UCSD Performance-based Skills Assessment (UPSA-B) for identifying functional milestones in schizophrenia.

Sensitivity and specificity of the UCSD Performance-based Skills Assessment (UPSA-B) for identifying functional milestones in schizophrenia.
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DOI:
10.1016/j.schres.2011.07.022
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发表时间:
2011-11
影响因子:
4.5
通讯作者:
Patterson, Thomas L.
Patterson, Thomas L.
中科院分区:
医学2区
文献类型:
--
作者:
Mausbach, Brent T.;Depp, Colin A.;Bowie, Christopher R.;Harvey, Philip D.;McGrath, John A.;Thronquist, Mary H.;Luke, James R.;Wolyniec, Paula S.;Pulver, Ann E.;Patterson, Thomas L.

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精神分裂症是一种高度虚弱的疾病,经常导致独立生活和就业的中断。然而,评估达到这些里程碑的功能能力的“黄金标准”方法仍然缺乏。在367名精神分裂症患者样本中,我们检验了简短的UCSD基于绩效的技能评估(UPSA-B)预测居住和就业状况的敏感性和特异性。在所有独立居住的个人中,75.9%的人在UPSA-B上的得分在78或以上,在所有非独立居住的个人中,59%的人在UPSA-B上的得分低于78。在有工作的人中,73.9%的人在UPSA-B上的得分高于82,而在没有就业的人中,57.8%的人得分低于82。这些结果扩展了用于验证UPSA-B的人口基础和功能里程碑,尽管未来的工作应该检查UPSA-B是否可以用作纵向研究成功可能性的决策辅助,例如在关键过渡阶段(住院后、停止支持的住房)。
Schizophrenia is a highly debilitating illness that often results in disruption to independent living and employment. However, “gold standard” methods of assessing functional abilities to achieve these milestones are still lacking. In a sample of 367 individuals with schizophrenia, we examined the sensitivity and specificity of the Brief UCSD Performance-based Skills Assessment (UPSA-B) to predict both residential and employment status. Of all individuals residing independently, 75.9% scored 78 or above on the UPSA-B, and of all individuals not residing independently, 59% scored below 78 on the UPSA-B. Of individuals who were employed, 73.9% scored above 82 on the UPSA-B, and of those not employed, 57.8% scored below 82. These results expand upon both the population base and functional milestones with which the UPSA-B is validated, although future work should examine whether the UPSA-B can be used as a decision aid in the likelihood of success in a longitudinal study, such as at critical transitions (post-hospitalization, cessation of supported housing).
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