REPRODUCIBILITY AND ACCURACY OF AIRWAY AREA BY ACOUSTIC REFLECTION
REPRODUCIBILITY AND ACCURACY OF AIRWAY AREA BY ACOUSTIC REFLECTION
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DOI：
10.1152/jappl.1984.57.3.777
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发表时间：
1984-01-01
影响因子：
3.3
通讯作者：
FREDBERG, JJ
中科院分区：
文献类型：
--
作者：
BROOKS, LJ;CASTILE, RG;FREDBERG, JJ
为了确定通过声反射（AAAR）测量气道面积的准确性和再现性，对人类志愿者、玻璃气道模型和离体犬气管的气管面积进行了重复测量。在10名成年男性中，X线测定的气管AAAR与气管面积的平均比值与1（1.06 ± 0.05）相比无显著差异。0.13 SD）。批内变异性为10 ±. 4%（CV），平均受试者内日间变异性为9 ±-。4%（CV）。一个定制的吸嘴是必要的AAAR的准确测量。与吸嘴结构差异相关的平均变异性为7 ± 0. 6%（CV）。使用玻璃气道模型研究了上气道和声门尺寸变化对气管AAAR测量的影响。在模型研究中，发现气管AAAR测量与近端气道大小或声门孔径的变化无关。1 cm 2和上呼吸道面积≤8平方厘米。在刚性壁玻璃模型中，气管面积被高估了20%。通过比较空气或凡士林包围的离体犬气管的声学和X线摄影测量，定性研究了气道壁刚度的影响。体外和体内AAAR测量准确性的差异可能是由于气道壁惯性的差异。AAAR的测量产生了一个准确的和可重复的结果，可能是临床上有用的中心气道geomentry的变化的无创检测。
To determine the accuracy and reproducibility of measurements of airway area by acoustic reflection (AAAR) repeated measurements were made of tracheal areas in human volunteers, glass airway models, and excised canine tracheae. In 10 adult males, the mean ratio of tracheal AAAR to tracheal areas determined roentgenographically was not significantly different from one (1.06 .+-. 0.13 SD). Within- run variability was 10 .+-. 4% (CV), mean intrasubject day-to-day variability was 9 .+-. 4% (CV). A custom-made mouthpiece is necessary for accurate measurements of AAAR. Mean variability related to differences in mouthpiece construction was 7 .+-. 6% (CV). The effect of variations in upper airway and glottic sizes on tracheal AAAR measurements was investigated using glass airway models. In model studies, tracheal AAAR measurements were found to be independent of changes in proximal airway size or glottic apertures .gtoreq. 1 cm2 and upper airway areas .ltoreq. 8 cm2. Tracheal area was overestimated by 20% in the rigid-walled glass models. The effects of airway wall ridigity were qualitatively investigated by comparing acoustic and roentgenographic measurements of excised canine tracheae surrounded by either air or petroleum jelly. Differences in the accuracy of measurements of AAAR in vitro and in vivo are probably due to differences in airway wall inertance. The measurement of AAAR yields an accurate and reproducible result that may be clinically useful for the noninvasive detection of changes in central airway geomentry.