Deformable Known Component Model-Based Reconstruction for Coronary CT Angiography.
Deformable Known Component Model-Based Reconstruction for Coronary CT Angiography.
复制标题
基于可变形已知组件模型的冠状动脉 CT 血管造影重建。
DOI：
10.1117/12.2255303
复制
发表时间：
2017
期刊：
影响因子：
--
通讯作者：
Stayman,JW
中科院分区：
文献类型：
--
作者：
Zhang,X;Tilley,S;Xu,S;Mathews,A;McVeigh,ER;Stayman,JW
目的：在冠状动脉CT血管造影中，对心脏植入患者的动脉粥样硬化检测仍然具有挑战性。起搏器的起搏电极或除颤器的引线部件可能在心脏区域中产生大量的晕染和条纹伪影，严重阻碍感兴趣斑块的可视化。我们提出了一种新的重建方法，该方法采用了可变形模型的金属导致消除金属伪影，并提高解剖可视化，即使在边界附近的component.MethodsThe建议的重建方法，简称为STF-dKCR，包括一种新的参数化的组成部分，集成变形，3D-2D预配准过程，估计组件的形状和位置，以及用于X射线传播通过该部件的多能前向模型，其中光谱特性被联合估计。在CBCT测试台上采集的心脏体模的物理数据上对该方法进行了测试。该体模包括模拟血管、模拟起搏电极导线的金属丝和附着在血管壁上的小特氟隆球体，模拟钙化斑块。所提出的方法也进行了比较，以传统的FBP重建和插值为基础的金属校正方法（FBP-MAR）。结果金属伪影在标准的FBP重建中提出的FBP-MAR和STF-dKCR显着减少，但只有STF-dKCR的方法显着提高了小聚四氟乙烯目标（2毫米内的金属丝）的可见性。Teflon珠的衰减从FBP的0.0166 mm-1和FBP-MAR的0.0301 mm-1提高到STF-dKCR的0.0481 mm-1，更接近预期的0.0414 mm-1。结论该方法有可能改善线状金属组件存在时冠状动脉CT血管造影中斑块的可视化。
PurposeAtherosclerosis detection remains challenging in coronary CT angiography for patients with cardiac implants. Pacing electrodes of a pacemaker or lead components of a defibrillator can create substantial blooming and streak artifacts in the heart region, severely hindering the visualization of a plaque of interest. We present a novel reconstruction method that incorporates a deformable model for metal leads to eliminate metal artifacts and improve anatomy visualization even near the boundary of the component.MethodsThe proposed reconstruction method, referred as STF-dKCR, includes a novel parameterization of the component that integrates deformation, a 3D-2D preregistration process that estimates component shape and position, and a polyenergetic forward model for x-ray propagation through the component where the spectral properties are jointly estimated. The methodology was tested on physical data of a cardiac phantom acquired on a CBCT testbench. The phantom included a simulated vessel, a metal wire emulating a pacing lead, and a small Teflon sphere attached to the vessel wall, mimicking a calcified plaque. The proposed method was also compared to the traditional FBP reconstruction and an interpolation-based metal correction method (FBP-MAR).ResultsMetal artifacts presented in standard FBP reconstruction were significantly reduced in both FBP-MAR and STF- dKCR, yet only the STF-dKCR approach significantly improved the visibility of the small Teflon target (within 2 mm of the metal wire). The attenuation of the Teflon bead improved to 0.0481 mm-1with STF-dKCR from 0.0166 mm-1with FBP and from 0.0301 mm-1with FBP-MAR – much closer to the expected 0.0414 mm-1.ConclusionThe proposed method has the potential to improve plaque visualization in coronary CT angiography in the presence of wire-shaped metal components.