Photodynamic therapy for focal ablation of the prostate
Photodynamic therapy for focal ablation of the prostate
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DOI：
10.1007/s00345-010-0554-2
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发表时间：
2010-10-01
影响因子：
3.4
通讯作者：
Emberton, M.
中科院分区：
文献类型：
--
作者：
Arumainayagam, Nimalan;Moore, C. M.;Emberton, M.
尽管处于临床开发的早期阶段，但光动力疗法（PDT）在原发性和放疗后前列腺癌的局部治疗中显示出希望。本文将回顾PDT的作用机制，以前的研究使用PDT治疗前列腺癌，包括新的血管作用的光敏剂的开发，以及PDT在提供局灶性治疗的潜在优势和劣势。
Although in early stages of clinical development, photodynamic therapy (PDT) shows promise in delivering focal treatment of both primary and post-radiotherapy prostate cancer. This article will review the mechanism of action of PDT, previous research using PDT for treating prostate cancer including the development of newer vascular-acting photosensitizers, and the potential advantages and disadvantages of PDT in delivering focal therapy.