Consolidation of sensorimotor learning during sleep
Consolidation of sensorimotor learning during sleep
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DOI：
10.1101/lm.1180908
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发表时间：
2008-11-01
影响因子：
2
通讯作者：
Margoliash, Daniel
中科院分区：
文献类型：
--
作者：
Brawn, Timothy P.;Fenn, Kimberly M.;Margoliash, Daniel
人们普遍认为睡眠有益于非陈述性记忆的巩固。然而，证据主要仅限于涉及死记硬背相同刺激或行为的任务，并且最近的研究结果对睡眠依赖性巩固的程度提出了质疑。我们展示了睡眠期间多模式感觉运动技能的巩固，该技能在不同的视觉空间虚拟环境中进行了训练和测试。参与者执行的任务需要与不断变化的视听刺激相协调，产生新颖的运动反应。训练后表现有所提高，醒来后记忆力下降，但在睡眠后恢复并稳定。这些结果将睡眠依赖性巩固的领域扩展到更复杂的适应性行为。
Consolidation of nondeclarative memory is widely believed to benefit from sleep. However, evidence is mainly limited to tasks involving rote learning of the same stimulus or behavior, and recent findings have questioned the extent of sleep-dependent consolidation. We demonstrate consolidation during sleep for a multimodal sensorimotor skill that was trained and tested in different visual-spatial virtual environments. Participants performed a task requiring the production of novel motor responses in coordination with continuously changing audio-visual stimuli. Performance improved with training, decreased following waking retention, but recovered and stabilized following sleep. These results extend the domain of sleep-dependent consolidation to more complex, adaptive behaviors.