Effect of combined laser acupuncture on knee osteoarthritis: a pilot study
Effect of combined laser acupuncture on knee osteoarthritis: a pilot study
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联合激光针灸治疗膝骨关节炎的效果：一项初步研究
DOI：
10.1007/s10103-007-0536-9
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发表时间：
2009-03-01
影响因子：
2.1
通讯作者：
Lao, Lixing
中科院分区：
文献类型：
--
作者：
Shen, Xueyong;Zhao, Ling;Lao, Lixing
我们的目的是评估10.6 μ m和650 nm激光联合照射治疗膝骨关节炎（OA）患者的疗效和安全性。40例OA患者被随机分配到活性激光组或安慰剂激光组（每组20例）。他们接受了积极或假激光治疗的Dubi穴（ST 35），共12个疗程。两组治疗2周后，西安大略和麦克马斯特大学（WOMAC）骨关节炎指数疼痛评分较基线变化有显著差异（P = 0.047）。主动激光治疗组的疼痛减轻率为49%，而安慰剂对照组仅为13%。但是，由于患者脱落率较高，无法分析4周评估。联合激光治疗似乎对膝关节OA患者有益。然而，由于安慰剂组患者的样本量较小且脱落率较高，因此需要进行大样本量临床试验，以进一步确定该器械的治疗效果。
Our objective was to assess the efficacy and safety of combined 10.6 mu m and 650 nm laser irradiation on patients with knee osteoarthritis (OA). Forty patients with OA were randomly allocated to an active laser group or to a placebo laser group (20 per group). They either received active or sham laser treatment at acupoint Dubi (ST 35) in a total of 12 sessions. There was significant difference between the two groups in the Western Ontario and McMaster Universities (WOMAC) osteoarthritis index pain score change from baseline after 2 weeks of treatment (P = 0.047). The pain reduction of the active laser treatment group was 49%, whereas that of the placebo control group was only 13%. However, due to the high patient drop-out rate, the 4-week assessment could not be analyzed. Combined laser treatment seems beneficial to patients with knee OA. However, due to the small sample size and the high drop-out rate of patients in the placebo group, a large sample-size clinical trial is warranted to determine further the therapeutic efficacy of the device.