Rhythms for Cognition: Communication through Coherence.
Rhythms for Cognition: Communication through Coherence.
复制标题
DOI：
10.1016/j.neuron.2015.09.034
复制
发表时间：
2015-10-07
期刊：
影响因子：
16.2
通讯作者：
Fries P
中科院分区：
文献类型：
--
作者：
Fries P
我认为，同步影响神经元群体之间的沟通。γ-波段（30-90 Hz）同步化足够快地调节兴奋，因此它逃脱了随后的抑制并有效地激活突触后神经元。同步还确保突触前激活模式以时间协调的方式到达突触后神经元。在突触后神经元处，多个突触前组会聚，例如表示不同的刺激。如果一个刺激被注意力所选择，它的神经元表现出更强和更高频率的伽马带同步。因此，关注的刺激表示选择性地夹带突触后神经元。这种夹带产生了一系列短暂的兴奋和较长的抑制，它们在突触前和突触后群体之间协调一致，以传递被关注的表征，并将竞争性输入拒之门外。主导的自下而上定向伽马波段影响由主导的自上而下定向α-β波段（8-20 Hz）影响控制。注意力本身以7-8 Hz的θ节律对刺激进行采样。因此，几种节奏及其相互作用使神经元通信有效，精确和选择性。
I propose that synchronization affects communication between neuronal groups. Gamma-band (30-90 Hz) synchronization modulates excitation rapidly enough so it escapes the following inhibition and activates postsynaptic neurons effectively. Synchronization also ensures that a presynaptic activation pattern arrives at postsynaptic neurons in a temporally coordinated manner. At a postsynaptic neuron, multiple presynaptic groups converge, e.g. representing different stimuli. If a stimulus is selected by attention, its neuronal representation shows stronger and higher-frequency gamma-band synchronization. Thereby, the attended stimulus representation selectively entrains postsynaptic neurons. The entrainment creates sequences of short excitation and longer inhibition that are coordinated between pre- and postsynaptic groups to transmit the attended representation and shut out competing inputs. The predominantly bottom-up directed gamma-band influences are controlled by predominantly top-down directed alpha-beta band (8-20 Hz) influences. Attention itself samples stimuli at a 7-8 Hz theta rhythm. Thus, several rhythms and their interplay render neuronal communication effective, precise and selective.