Parallel pathways for vocal learning in basal ganglia of songbirds
Parallel pathways for vocal learning in basal ganglia of songbirds
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DOI：
10.1038/nn.2472
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发表时间：
2010-02-01
影响因子：
25
通讯作者：
Altenau, Brie
中科院分区：
文献类型：
--
作者：
Bottjer, Sarah W.;Altenau, Brie
皮质核 LMAN（巢前球外侧大细胞核）提供基底神经节通路的输出，这对于幼鸟的声音学习是必需的。 LMAN 的壳子区域（LMAN(shell)）产生可能有助于特定学习相关功能的循环。我们发现 LMAN(shell) 通路中的损伤不会立即破坏发声行为，但会阻止稳定发声序列和模仿发声能力的发展。
The cortical nucleus LMAN (lateral magnocellular nucleus of the anterior nidopallium) provides the output of a basal ganglia pathway that is necessary for vocal learning in juvenile songbirds. The shell subregion of LMAN (LMAN(shell)) gives rise to recurrent loops that may subserve specific learning-related functions. We found that lesions in the LMAN(shell) pathway caused no immediate disruption of vocal behavior, but prevented the development of stable vocal sequences and the ability to imitate vocal sounds.